A pathologic condition is described, characterized by rampant necrosis of gingival mucosa, periodontium, and related osseous structures associated with systemic infection with the human immunodeficiency virus (HIV). It is believed that this condition is an extension beyond the normal clinical course of HIV-periodontitis (HIV-P) and manifests itself in three progressive stages: (1) HIV-associated gingivitis, (2) HIV-P, and (3) an extension of HIV-P to osseous necrosis. Two cases of osseous destruction attending HIV-P are reported, one of which led to initial diagnosis of HIV infection. They represent the final stage of disease progression with localized necrosis of gingiva, periodontium, and alveolar bone.
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http://dx.doi.org/10.1016/0030-4220(90)90214-d | DOI Listing |
Pheochromocytoma (PHEO) currently is considered to be malignant due to metastatic potential. One of the most common familial forms of PHEO is multiple endocrine neoplasia syndrome (MEN) type 2. The penetrance of PHEO in MEN2 syndrome is up to 50% of cases.
View Article and Find Full Text PDFForensic Sci Int
January 2025
Department of Chemistry Government College University, Lahore, Pakistan. Electronic address:
Skeletal remains are the only source of the genetic material of decomposed organisms or once-lived species. Unlike, soft tissues they are highly mineralized, and their anatomical and morphological structure prevents their deformation in the presence of adverse environmental factors. Therefore, bones and teeth protect the Deoxyribonucleic Acid (DNA) inside them.
View Article and Find Full Text PDFPediatr Radiol
January 2025
Department of Pediatric Genetics, Istanbul University-Cerrahpaşa, Cerrahpasa Medical Faculty, 34098, Cerrahpasa, Istanbul, Turkey.
Background: Heterozygous TRPV4 mutations cause a group of skeletal dysplasias characterized by short stature, short trunk, and skeletal deformities.
Objective: The aim of this study is to compare the natural history of clinical and radiologic features of patients with different TRPV4-related skeletal dysplasias.
Materials And Methods: Thirteen patients with a mutation in TRPV4 were included in the study, and 11 were followed for a median of 6.
BMC Med Imaging
January 2025
Faculty of Medicine, Department of Obstetrics and Gynecology, Erciyes University, Yenidogan Neighborhood, Turhan Baytop Street No:1, Kayseri, 38280, Turkey.
Aim: This study aimed to evaluate the effect of maternal vitamin D use during intrauterine life on fetal bone development using ultrasonographic image processing techniques.
Materials And Methods: We evaluated 52 pregnant women receiving vitamin D supplementation and 50 who refused vitamin D supplementation. Ultrasonographic imaging was performed on the fetal clavicle at 37-40 weeks of gestation.
Anal Chem
January 2025
Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool L69 3BX, U.K.
Reports of proteins in fossilized bones have been a subject of controversy in the scientific literature because it is assumed that fossilization results in the destruction of all organic components. In this paper, a novel combination of analytical techniques is used to address this question for an exceptionally well-preserved sacrum excavated from the Upper Cretaceous strata of the South Dakota Hell Creek Formation. Cross-polarized light microscopy (XPol) shows birefringence consistent with collagen presence.
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