AI Article Synopsis
- Fish can sense very low concentrations of dangerous marine toxins like tetrodotoxin (TTX) and saxitoxin (STX) using specialized taste receptors.
- Research indicates that the receptors for TTX and STX are different from those that detect normal feeding compounds such as amino acids and bile acids.
- TTX and STX compete with substances like quinine and strychnine, hinting at a possible antidotal relationship between them.
Article Abstract
Fish detect extremely low levels of marine toxins tetrodotoxin (TTX) and saxitoxin (STX) via the specialized gustatory receptor(s). Physiological and pharmacological studies show that receptor(s) for TTX and STX are distinct from those which detect feeding stimulant amino acids and bile acids, and that TTX and STX do not share the same receptor populations, while interacting with quinine and strychnine in a competitive fashion suggestive of an antidotal relationship.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229235 | PMC |
| http://dx.doi.org/10.3390/md9112283 | DOI Listing |
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