A 67-year-old male patient noticed a foreign body sensation following a trivial trauma to the sole of the left foot approximately 4 months before presentation. The existing skin alteration had been self-treated with pumice stone and an unidentifiable wart tincture. The examination revealed an approximately 2 cm in diameter macula on the left heel with a zonal construction. The periphery was formed by a polycyclic dark brown ring which enclosed a reddish skin colored macula with several minute erosions. Dermatoscopy revealed an unspecific pattern with polymorphic vessels in the center. The peripheral ring showed radially running streaks as well as a parallel track-like pattern in one region. Histology revealed this to be an acral melanoma. A melanoma should always be included in the differential diagnostic considerations of atypical acral lesions. A biopsy should always be carried by unclear clinical and light microscopical findings out to enable a final diagnosis.
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http://dx.doi.org/10.1007/s00105-011-2272-0 | DOI Listing |
Healthcare (Basel)
January 2025
Emergency Department, CHU UCL Namur, 5530 Yvoir, Belgium.
Penetrating orbit injury is a rare but complex and life-threatening occurrence that may easily be overlooked. Management in the emergency department requires an early multidisciplinary approach but still lacks standard guidelines. This narrative review aims to provide a systematic approach to the management of penetrating orbital injuries for emergency clinicians.
View Article and Find Full Text PDFJ Sci Med Sport
January 2025
Department of Mathematics & Statistics, University of Otago, New Zealand.
Objectives: Knee braces were introduced to sports 30 years ago. However, knee brace use for non-contact anterior cruciate ligament injury prevention intervention remains contentious due to concerns about performance hindrances. Since knee brace use is a potential modifiable risk factor, we aimed to investigate the effect of discounting and continued functional knee brace (FKB) on lower extremity power-vertical jump (VJ), acceleration, speed, and agility performance.
View Article and Find Full Text PDFCureus
December 2024
Orthopaedic and Spine Surgery, National Institute of Traumatology and Orthopaedic Rehabilitation (NITOR), Dhaka, BGD.
Introduction: Ankylosing spondylitis (AS), a chronic inflammatory spondyloarthropathy affecting the spine, progressively leads to increased spinal stiffness. This condition increases the risk of spine fractures in patients, even from trivial injuries. The process of slow bone formation within the ligaments of the spine and the fusion of the spinal diarthrosis contribute to the most prominent symptom of progressive stiffness of joints, predominantly affecting the spine and sacroiliac joints.
View Article and Find Full Text PDFJ Orthop Case Rep
December 2024
Department of Orthopaedics, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India.
Introduction: Infected gap non-union is a serious complication seen in cases of diaphyseal fracture of forearm bones. It carries high morbidity in the form of severe functional impairment and poses a challenge to treat due to the complex anatomical relationship and articulations involved. Though there are multiple treatment options available, there are no guidelines for its management.
View Article and Find Full Text PDFNonsteroidal anti-inflammatory drugs (NSAIDs) are the most widely used medications for the management of chronic pain; however, they are associated with numerous gastrointestinal (GI) adverse events. Although many mechanisms have been suggested, NSAID-induced enteropathy has been thought to be primarily due to inhibition of both cyclooxygenases (COX) -1 and -2, which results in suppression of prostaglandin synthesis. Yet surprisingly, we found that concomitant postnatal deletion of and over 10 months failed to cause intestinal injury in mice unless they were treated with naproxen or its structural analog, phenylpropionic acid, which is not a COX inhibitor.
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