Introduction: Baseline data for physical condition are not available for adolescents in Cali, Colombia.
Objective: This study aimed to develop representative age- and sex- specific percentile baseline data for physical condition (mL.kg-1.min-¹) for urban adolescents aged 10-16 years. Materials and methods. The sample (n=1,773) consisted of 865 males and 908 females from the cross-sectional population survey, the IFRECNTEC Study (Identification of Risk Factors of Non-Transmissible Adult Chronic Diseases in School-age Populations in the City of de Cali), for whom the data for physical condition were recorded. Smoothed age- and sex- specific 5th, 25th, 50th, 75th, 90th and 95th centile values where derived using least mean squares regression analysis.
Results: Percentile-based reference data for physical condition were presented for adolescent Colombian boys and girls for the first time. In males, the p50 of the PWC-170 (VO2max) ranged 49-43, and in females 52-40. A decreasing trend (~10%) in the p50 was seen in both sexes over 16 years of age. In general, more heterogeneity was present among males than females in terms of physical aptitude through VO2max test.
Conclusion: The results established a baseline level of physical condition in adolescents that can be interpreted as an indicator of future cardiovascular health. They also recommend that the physical condition of Colombian adolescents must be improved to protect against cardiovascular disease in adulthood.
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http://dx.doi.org/10.1590/S0120-41572011000200012 | DOI Listing |
J Clin Invest
January 2025
Center for Inherited Myology Research, Virginia Commonwealth University, Richmond, United States of America.
Background: Myotonic dystrophy type 1 (DM1) is a multisystemic, CTG repeat expansion disorder characterized by a slow, progressive decline in skeletal muscle function. A biomarker correlating RNA mis-splicing, the core pathogenic disease mechanism, and muscle performance is crucial for assessing response to disease-modifying interventions. We evaluated the Myotonic Dystrophy Splice Index (SI), a composite RNA splicing biomarker incorporating 22 disease-specific events, as a potential biomarker of DM1 muscle weakness.
View Article and Find Full Text PDFRheumatol Ther
January 2025
Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Introduction: Prescribable digital health applications (DiGAs) present scalable solutions to improve patient self-management in rheumatology, however real-world evidence is scarce. Therefore, we aimed to assess the effectiveness, usage, and usability of DiGAs prescribed by rheumatologists, as well as patient satisfaction.
Methods: The DiGAReal registry includes adult patients with rheumatic conditions who received a DiGA prescription.
Int Urol Nephrol
January 2025
Department of Nursing, China Medical University, Shenyang, Liaoning, China.
Purpose: To conduct a scoping review of the related research on cognitive frailty (CF) in maintenance hemodialysis (MHD) patients, so as to provide a basis for early diagnosis, treatment and intervention of CF in MHD patients.
Methods: Utilizing a scoping review approach, we searched PubMed, Embase, The Cochrane Library, Web of Science, CINAHL, the China Biological Medicine Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu (VIP) for literature on CF in MHD patients up to October 20, 2024. Two researchers conducted independent screening and data extraction of the literature's fundamental characteristics.
Inflammation
January 2025
Department of Chemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Parkinson's disease (PD) stands as the sec most prevalent incapacitating neurodegenerative disorder characterized by deterioration of dopamine-producing neurons in the substantia nigra. Coenzyme Q10 (CoQ10) has garnered attention as a potential antioxidant, anti-inflammatory agent and enhancer of mitochondrial complex-I activity. This study aimed to examine and compare the effectiveness of liposomal and non-encapsulated CoQ10 in rotenone induced-PD mouse model over a 21-day treatment duration.
View Article and Find Full Text PDFArch Womens Ment Health
January 2025
Department of Psychology, University of Wisconsin-Madison, 1202 W. Johnson St, Madison, WI, 53706, USA.
Purpose: Given the lack of available and effective interventions to address the detrimental consequences of perinatal exposure to intimate partner violence (IPV) on maternal mental health, and reported very low access to IPV-related mental health services in Mexico, we examined the feasibility and efficacy of a culturally adapted, virtual, brief group psychosocial intervention designed to improve maternal mental and physical health and reduce IPV revictimization for pregnant women exposed to IPV. In this pilot randomized controlled trial, we evaluated maternal outcomes after participation in the Pregnant Moms' Empowerment Program (PMEP) in Mexico.
Methods: Women were recruited from social service agencies and health centers in the community, as well as social media advertisements that targeted pregnant women living in Mexico.
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