Notch-Delta signaling is indispensable for somitogenesis, which controls the vertebrate segmentation during embryonic development. Several theoretical models have been proposed to explain this interesting process. In zebrafish somitogenesis, genes her1, her7, delta, and their proteins plays the important roles. However, an auto-repression model with time delay involved only by her1/her7 is able to explain zebrafish somitogenesis. This paper will systematically study the dynamics of this model. Specifically we investigate its stability, bifurcation (oscillation), and stability of oscillation. First, the conditions for both stability and bifurcation are presented based on the linearized model. Then three indices for bifurcation of this nonlinear model are derived by using linear functional operator analysis. Finally, the numerical simulations are carried out to illustrate the theoretical results developed in this study.
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http://dx.doi.org/10.1109/TNB.2011.2178429 | DOI Listing |
Chaos
January 2025
Department of Mathematics, Indian Institute of Technology Patna, Patna 801103, India.
Human immunodeficiency virus (HIV) manifests multiple infections in CD4+ T cells, by binding its envelope proteins to CD4 receptors. Understanding these biological processes is crucial for effective interventions against HIV/AIDS. Here, we propose a mathematical model that accounts for the multiple infections of CD4+ T cells and an intracellular delay in the dynamics of HIV infection.
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January 2025
Department of Mathematics, National Institute of Technology Silchar, Silchar, Assam 788010, India.
This study introduces a five-compartment model to account for the impacts of vaccination-induced recovery and nonlinear treatment rates in settings with limited hospital capacity. To reflect real-world scenarios, the model incorporates multiple reinfections in both vaccinated and recovered groups. It reveals a range of dynamics, including a disease-free equilibrium and up to six endemic equilibria.
View Article and Find Full Text PDFEcol Evol
January 2025
CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences Yantai China.
Estuaries are ecologically sensitive areas influenced by river regulation. Knowledge of how marine megabenthos responds to river regulation and artificial flooding events remains limited. The study aims to provide a comprehensive understanding of the impacts of river regulation on marine megabenthic fauna.
View Article and Find Full Text PDFEntropy (Basel)
December 2024
School of Modern Posts, Xi'an University of Posts and Telecommunications, Xi'an 710061, China.
To investigate the dynamic complexity of chain-to-chain output decisions in a closed-loop supply chain system of cross-border e-commerce (CBEC), this study decomposes the system into four product-market (PM) chains, based on the e-commerce platform's information-sharing strategy and the manufacturer's selected logistics mode (direct mail or bonded warehouse). By combining game theory with complex systems theory, discrete dynamic models for output competition among PM chains under four scenarios are constructed. The Nash equilibrium solution and stability conditions of the models are derived according to the principles of nonlinear dynamics.
View Article and Find Full Text PDFEntropy (Basel)
November 2024
School of Statistics and Data Science, Nanjing Audit University, Nanjing 211815, China.
With the widespread application of chaotic systems in many fields, research on chaotic systems is becoming increasingly in-depth. This article first proposes a new dynamic model of financial risk contagion based on financial principles and discusses some basic dynamic characteristics of the new chaotic system, such as equilibrium points, dissipativity, Poincaré diagrams, bifurcation diagrams, etc. Secondly, with the consideration of privacy during data transmission, the method was designed to protect the privacy of controlled systems in finite time based on perturbation.
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