[Peroperative anaphylactic shock in children: management and evaluation].

Ann Fr Anesth Reanim

Service d'anesthésie réanimation, université Rennes-I, hôpital Pontchaillou, CHU de Rennes, France.

Published: January 2012

Anaphylactic shock is the most severe manifestation of hypersensitivity, whether of allergic origin or not. In the operating theatre, anaphylactic shock is rare in paediatric patients and latex allergy is still the major cause of allergy. Whatever the cause and mechanism of the reaction, its treatment should be started as early as possible: a high level of suspicion is thus necessary to establish a diagnosis as early as possible. Symptomatic treatment is well codified. The results of blood sampling at the time of the reaction and of allergic tests performed a few weeks later will enable a definitive diagnosis to be made and appropriate recommendations (medical alert card) to be given to the patients and its parents.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annfar.2011.11.005DOI Listing

Publication Analysis

Top Keywords

anaphylactic shock
12
[peroperative anaphylactic
4
shock children
4
children management
4
management evaluation]
4
evaluation] anaphylactic
4
shock severe
4
severe manifestation
4
manifestation hypersensitivity
4
hypersensitivity allergic
4

Similar Publications

This report describes the development of oesophagitis and oesophageal stricture in a dog secondary to anaphylaxis. A 9-month-old male entire Brussels Griffon presented in anaphylactic shock after exposure to Hymenoptera species (Sp). The dog had a history of an anaphylactic reaction after exposure to Hymenoptera, successfully managed with antihistamines and dexamethasone.

View Article and Find Full Text PDF

Antigenic determinants underlying IgE-mediated anaphylaxis to peanut.

J Allergy Clin Immunol

January 2025

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN; Department of Pharmacology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN.

Background: Studies of human IgE and its targeted epitopes on allergens have been very limited. We have an established method to immortalize IgE encoding B cells from allergic individuals.

Objective: To develop an unbiased and comprehensive panel of peanut-specific human IgE mAbs to characterize key immunodominant antigenic regions and epitopes on peanut allergens to map the molecular interactions responsible for inducing anaphylaxis.

View Article and Find Full Text PDF

Background: The incidence of anaphylaxis is increasing worldwide. However, there is a lack of data on anaphylaxis trends in Türkiye. This study aims to analyse trends in anaphylaxis-related emergency department (ED) visits and examines factors associated with fatal anaphylaxis in Türkiye.

View Article and Find Full Text PDF

Structural determinants of peanut induced anaphylaxis.

J Allergy Clin Immunol

January 2025

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN; Department of Pharmacology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN. Electronic address:

Background: Human monoclonal IgE antibodies recognizing peanut allergens have recently become available, but we lack a detailed understanding of how these IgEs target allergens.

Objective: To determine the molecular details of the antibody-allergen interaction for a panel of clinically important human IgE monoclonal antibodies and to develop strategies to disrupt disease causing antibody-allergen interactions.

Methods: We identified candidates from a panel of epitope binned human IgE monoclonals that recognize two important and homologous peanut allergens, Ara h 2 and Ara h 6.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!