Number of graphene layers exhibiting an influence on oxidation of DNA bases: analytical parameters.

Anal Chim Acta

Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.

Published: January 2012

AI Article Synopsis

  • The article studies how different layers of graphene affect the oxidation of adenine and guanine.
  • It finds that few-layer graphene shows a much higher sensitivity in detecting these compounds compared to single-layer graphene.
  • These results could greatly impact the development of graphene-based genosensors for better detection technologies.

Article Abstract

This article investigates the analytical performance of double-, few- and multi-layer graphene upon oxidation of adenine and guanine. We observed that the sensitivity of differential pulse voltammetric response of guanine and adenine is significantly higher at few-layer graphene surface than single-layer graphene. We use glassy carbon electrode as substrate coated with graphenes. Our findings shall have profound influence on construction of graphene based genosensors.

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http://dx.doi.org/10.1016/j.aca.2011.10.054DOI Listing

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