Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3145
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Translating clinical research findings into daily medical practice is a complex procedure and subject to multiple impacts. Studies sponsored by drug manufacturers produce positive results more frequently than would be expected by chance alone; positive studies have a better chance to be published than negative ones. There is a lack of effective implementation strategies for medical guidelines. The mismatch of study population and own patients renders the generalizability of study results difficult. Other confounding factors in head-to-head studies are drug comparisons that do not conform to the gold standard, non-equivalent dosages and study duration. To solve these problems clinical research must pick up questions and problems from daily medical care. Studies independent of drug companies should be funded with public money, and health care research needs public support. Access to study protocols and data must be open to the public.
Download full-text PDF |
Source |
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http://dx.doi.org/10.1016/j.zefq.2011.10.027 | DOI Listing |
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