Two cases of chronic pelvic pain of unknown etiology with symptoms referable to the low abdominal wall are presented. These patients are often difficult to manage because of multiple causes and multiple pathways for pain transmission from the pelvis. In these cases, the patients' complaints were refractory to medication management, as well as diagnostic and therapeutic nerve blockade. After careful evaluation, a successful trial of peripheral nerve stimulation was followed by permanent implantation of low abdominal subcutaneous leads and a pulse generator device. The patients reported excellent relief of their chronic pelvic pain. The use of neuromodulation via peripheral stimulation deserves further investigation as an alternative to spinal cord stimulation for chronic pelvic pain.
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http://dx.doi.org/10.1111/j.1525-1403.2008.00176.x | DOI Listing |
Radiol Case Rep
March 2025
Department of Radiology, University Hospitals Cleveland Medical Center, 11100 Euclid Avenue Cleveland, OH 44106, USA.
Endometriosis is described as the proliferation of endometrial tissue outside of the uterus. This most frequently occurs within the pelvis and is a common cause of chronic pelvic pain in women of reproductive age. Rarely, endometriosis can manifest outside of the pelvis and can uncommonly involve the musculoskeletal and peripheral nervous systems.
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January 2025
Division of Vascular Surgery, Department of Surgery, College of Medicine, King Saud University, Riyadh 11322, Saudi Arabia.
Phlebolith is a term that refers to round-shaped calcified thrombi commonly located in the pelvic region. The occurrence of dense, linear calcifications or phlebolith-like formations within the soft tissues of the lower extremities, particularly in the superficial femoral, greater saphenous, or popliteal veins, is rare. This study presents the case of a 73-year-old woman who was being evaluated for postmenopausal bleeding.
View Article and Find Full Text PDFOrthop Surg
January 2025
Orthopedic Department, Peking University Third Hospital, Beijing, China.
Background And Importance: Ankylosing spondylitis (AS) is a systemic chronic inflammatory disease. Andersson lesion (AL) is a late complication of advanced AS. Idiopathic spinal cord hernia (ISCH) is a rare disorder of the spinal cord.
View Article and Find Full Text PDFCell Biosci
January 2025
Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, 26 Yuancun Erheng Road, Guangzhou, 510655, Guangdong, China.
Background: Intratumoral heterogeneity emerges from accumulating genetic and epigenetic changes during tumorigenesis, which may contribute to therapeutic failure and drug resistance. However, the lack of a quick and convenient approach to determine the intratumoral epigenetic heterogeneity (eITH) limit the application of eITH in clinical settings. Here, we aimed to develop a tool that can evaluate the eITH using the DNA methylation profiles from bulk tumors.
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January 2025
Department of Obstetrics and Gynecology, Ribeirão Preto Medical School of the University of São Paulo-USP, Ribeirão Preto, Brazil.
This study aimed to report the incidence of chronic pelvic pain in women 12 to 24 months postpartum, to identify the independently associated factors, and to conduct a causal inference with C-section as the exposure. This was a cross-sectional study nested within 2 distinct prospective cohorts from 2 Brazilian cities. Chronic pelvic pain was the dependent variable.
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