Purpose: To assess success and intervention rates for full-thickness skin grafts in the periocular region without the use of a sutured bolster dressing.
Methods: A clinical assessment of the long-term outcome in consecutive patients who underwent skin-grafting procedures without a bolstered dressing between 2003 and 2009 under a single surgeon (BP). All patients were independently clinically evaluated by two surgeons to assess final graft outcome. Data was collected on demographics, surgical indication, surgical technique, follow-up time and complications. The final clinical evaluation assessed graft thickness, color, contracture and lid position. Patient satisfaction was assessed using a visual analogue scale. Mean follow-up time was 27 months.
Results: Clinical review was possible in 35 out of 47 grafts carried out during the study period. There were no cases of postoperative graft ischemia or failure. Hematoma not affecting the final outcome occurred in two grafts and graft contraction requiring intervention occurred in only one patient. Patient satisfaction was high with an average score of 9/10.
Conclusion: We report a high success rate for periocular skin grafts without the use of a bolstered dressing. The use of a bolster increases operating time, postoperative care and is possibly less acceptable to the patient. We suggest that that in most cases the use of a bolster is not necessary for periocular skin grafts.
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http://dx.doi.org/10.3109/01676830.2011.638096 | DOI Listing |
J Clin Med
December 2024
Dermatology Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, 3004-561 Coimbra, Portugal.
: Reperfusion is a major determinant of skin graft viability. The contributions of the perfusion status of the wound bed, wound margin, and donor skin to the success of the skin graft are unclear. We aimed to evaluate the relationship between perfusion variables and graft necrosis extension on the scalp and lower limb.
View Article and Find Full Text PDFBioengineering (Basel)
December 2024
Paediatric Burn Center, Children's Skin Center, Department of Surgery, University Children's Hospital Zurich, Lenggstrasse 30, 8008 Zurich, Switzerland.
For pediatric patients with full-thickness burns, achieving adequate dermal regeneration is essential to prevent inelastic scars that may hinder growth. Traditional autologous split-thickness skin grafts alone often fail to restore the dermal layer adequately. This study evaluates the long-term effect of using a NovoSorb Biodegradable Temporizing Matrix (BTM) as a dermal scaffold in four pediatric patients, promoting dermal formation before autografting.
View Article and Find Full Text PDFBiomolecules
November 2024
Laboratory of Animal Research Center (LARC), Qatar University, Doha 2713, Qatar.
Atopic dermatitis (AD) is a chronic inflammatory skin disease with rising prevalence, marked by eczematous lesions, itching, and a weakened skin barrier often tied to filaggrin gene mutations. This breakdown allows allergen and microbe entry, with thymic stromal lymphopoietin (TSLP) playing a crucial role by activating immune pathways that amplify the allergic response. TSLP's central role in AD pathogenesis makes it a promising therapeutic target.
View Article and Find Full Text PDFHepatol Commun
November 2024
Department of Medicine, University of California, San Diego, La Jolla, California, USA.
Background: Liver fibrosis is caused by chronic toxic or cholestatic liver injury. Fibrosis results from the recruitment of myeloid cells into the injured liver, the release of inflammatory and fibrogenic cytokines, and the activation of myofibroblasts, which secrete extracellular matrix, mostly collagen type I. Hepatic myofibroblasts originate from liver-resident mesenchymal cells, including HSCs and bone marrow-derived CD45+ collagen type I+ expressing fibrocytes.
View Article and Find Full Text PDFClin Oral Investig
January 2025
Department of Cranio- and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany.
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