Preparation and characterization of imogolite/DNA hybrid hydrogels.

Biomacromolecules

Institute for Materials Chemistry and Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.

Published: January 2012

AI Article Synopsis

  • Imogolite is a clay mineral found in volcanic ash soils, which can be combined with DNA to create innovative hybrid hydrogels.
  • These hydrogels are formed through strong interactions between imogolite's aluminol groups and DNA's phosphate groups, with varying feed ratios affecting their properties.
  • The hybrid gels exhibit different physical structures in dispersion (fibrous imogolite) vs. gel state (3D network), with the optimal DNA content achieved at an equivalent molar ratio of imogolite and DNA.

Article Abstract

Imogolite is one of the clay minerals contained in volcanic ash soils. The novel hybrid hydrogels were prepared from imogolite nanofibers and DNA by utilizing strong interaction between the aluminol groups on imogolite surface and phosphate groups of DNA. The hybrid hydrogels of imogolite and DNA were prepared in various feed ratios, and their physicochemical properties and molecular aggregation states were investigated in both dispersion and gel states. The maximum DNA content in the hybrid gels was shown in equivalent molar ratio of imogolite and DNA. The physical properties of the hybrid gels were changed by varying DNA blend ratios. In the dispersion state, the hybrid gels showed a fibrous structure of imogolite, whereas a continuous network structure was observed in pure imogolite, indicating that the hybrid with DNA enhanced the dispersion of imogolite. In the gel state, DNA and imogolite nanofibers formed a 3D network structure.

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Source
http://dx.doi.org/10.1021/bm201616mDOI Listing

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