We report our experience with island cartilage tympanoplasty in revision cases and assess the anatomical and functional outcomes. We conducted a retrospective chart review at a tertiary referral center for patients who underwent revision tympanoplasty using cartilage with the island technique without mastoidectomy between January 2002 and December 2008. 60 cases were included in the study and successful closure without reperforation was obtained in 52 of 60 patients (87%). Three failed cases underwent a subsequent procedure endaurally with a positive result (92% accumulated success rate). Average postoperative pure-tone audiometry air-bone gap was 13 ± 7 dB compared with 21 ± 11 dB preoperatively (p = 0.004). An overall postoperative air-bone gap of 20 dB or less was achieved in 46 of the 60 patients (76.7%). Tympanoplasty with island cartilage grafting is a reliable procedure for revision cases with excellent anatomic results as well as significant improvement of hearing.
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http://dx.doi.org/10.1007/s00405-011-1875-5 | DOI Listing |
Osteoarthr Cartil Open
March 2025
Pain Centre Versus Arthritis and Academic Unit of Injury, Recovery and Inflammation Sciences, University of Nottingham, UK.
Objectives: Histological osteochondral characteristics of inflammation, fibrosis, vascularity, cartilage islands, vessels entering cartilage, thickened trabeculae and cysts are associated with bone marrow lesions (BMLs) in human knee osteoarthritis (OA). We identified and developed a method for scoring comparable pathology in two rat OA knee pain models.
Methods: Rats (n = 8-10 per group) were injected with monoiodoacetate (MIA) or saline, or underwent meniscal transection (MNX) or sham surgery.
BMC Emerg Med
December 2024
Department of Emergency Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, No. 539, Zhongxiao Road, East District, Chiayi City, 600, Taiwan.
Background: In emergency settings, difficult intubations often occur unexpectedly despite pre-intubation assessments. Traditional glottic view scoring systems for direct laryngoscope may not apply to video laryngoscopy. With video laryngoscopy, the vertical location of the glottis on the monitor can be clearly defined.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Center of Marine Sciences (CCMAR), University of Algarve, 8005-139 Faro, Portugal.
Matrix Gla protein (MGP) is a vitamin K-dependent γ-carboxylated protein that was initially identified as a physiological inhibitor of ectopic calcification, primarily affecting cartilage and the vascular system. Mutations in the gene were found to be responsible for the Keutel syndrome, a condition characterized by abnormal calcifications in the cartilage, lungs, brain, and vascular system. has been shown to be dysregulated in several tumors, including cervical, ovarian, urogenital, and breast cancers.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Centro Hospitalar Tondela Viseu, Viseu, PRT.
Mesenchymal chondrosarcoma (MCS) is a rare, aggressive subtype of chondrosarcoma characterized by biphasic histology, often misdiagnosed due to its rarity and histological resemblance to other small round cell tumors. It predominantly affects adolescents and young adults. We report a 27-year-old male presenting with a progressively enlarging, painless mass in the right inframammary region, initially attributed to muscular strain.
View Article and Find Full Text PDFBraz J Otorhinolaryngol
December 2024
Ege University Faculty of Medicine, Department of Otorhinolaryngology, Izmir, Turkey.
Objective: This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.
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