Purpose Of Review: Since its advent, implantable cardioverter defibrillator (ICD) intra-operative defibrillation testing (DFT) has been a standard practice to confirm its optimal configuration. However, due to advances in device and lead technology, which now facilitate successful device implantation, and due to growing number of ICD primary prevention patients, the need for DFT has recently been questioned. The purpose of this review is to summarize the pro and contra DFT arguments, according to benefits, risk and clinical relevance, trying to identify the candidates for whom DFT is really indicated.
Recent Findings: There is an ongoing debate on the need for DFT at ICD implant due to significant DFT-related complications; recently, many electrophysiologists have chosen not to perform DFT in many cases. Recent literature findings document large differences of practice between different centres and countries. In particular, there has been major debate and concern over performing DFT in patients with heart failure, indicated for CRT-D implants (cardiac resynchronization therapy with defibrillator).
Summary: Due to the potential for serious complications during DFT and expanding primary prevention ICD candidates, we agree with the growing tendency not to routinely perform DFT at implant, as the risks may overweigh the benefits.
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http://dx.doi.org/10.1097/HCO.0b013e32834dc366 | DOI Listing |
ACS Nano
January 2025
Institute of Physical Chemistry, Karlsruhe Institute of Technology, Kaiserstraße 12, Karlsruhe 76131, Germany.
Atomically precise clusters such as [Pt(CO)(PPh)] ( = 1,2) (PPh is triphenylphosphine) are known as precursors for making oxidation catalysts. However, the changes occurring to the cluster upon thermal activation during the formation of the active catalyst are poorly understood. We have used a combination of hybrid mass spectrometry and surface science to map the thermal decomposition of [Pt(CO)(PPh)](NO).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.
Heterogeneous catalysts have emerged as a potential key for closing the carbon cycle by converting carbon dioxide (CO) into value-added chemicals. In this work, we report a highly active and stable ceria (CeO)-based electronically tuned trimetallic catalyst for CO to CO conversion. A unique distribution of electron density between the defective ceria support and the trimetallic nanoparticles (of Ni, Cu, Zn) was established by creating the strong metal support interaction (SMSI) between them.
View Article and Find Full Text PDFACS Nano
January 2025
Department of Materials Science and Engineering, Incheon National University, Incheon 22012, Korea.
HfO-based thin films have garnered significant interest for integrating robust ferroelectricity into next-generation memory and logic chips, owing to their applicability with modern Si device technology. While numerous studies have focused on enhancing ferroelectric properties and understanding their fundamentals, the fabrication of ultrathin HfO-based ferroelectric films has seldom been reported. This study presents the concept of atomic-level stoichiometry control of ferroelectric HfZrO films by examining the molecular-level interactions of precursor molecules in the atomic layer deposition (ALD) process through theoretical calculations.
View Article and Find Full Text PDFJ Mol Model
January 2025
State Key Laboratory of Polyolefins and Catalysis, Shanghai, 200062, People's Republic of China.
Context: This study aims to reveal the reaction mechanisms of H and O on the NiO(100) and Ce-doped NiO(100) surfaces using the density functional theory (DFT) combined with the on-site Coulomb correction (DFT + U) method. It was found that H and O react favorably on the reduced surfaces of both materials. However, after the oxygen vacancy is filled, the activation energy for the reaction between H₂ and lattice oxygen increases.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Advanced Membranes and Porous Materials Center, Division of Physical Science and Engineering, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia.
Understanding how structural modifications affect the photophysics of organic linkers is crucial for their integration into metal-organic frameworks (MOFs) for light-driven applications. This study explores the impact of varying the amine functional group position on two terephthalic acid derivatives─linker and linker ─by investigating their photophysics through a combination of steady-state and ultrafast laser spectroscopy and time-dependent density functional theory (TD-DFT) calculations. With tetrahydrofuran as the solvent, time-correlated single-photon counting revealed a 2-fold increase in the S excited-state lifetime of the molecule with the amine group at the meta position compared with that of the molecule with the amine group at the ortho position.
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