Aims: This study was undertaken to determine the effect of step-curing, ramp curing, single intensity on the effectiveness of cure and polymerization shrinkage of composite resin. The influence of filler loading on the effectiveness of cure and polymerization shrinkage of composite resin was investigated.
Materials And Methods: In this study, a total of 80 specimens divided into four groups were used. Group I - specimens cured with the step-cure mode. Group II - specimens cured with single high intensity. Group III - specimens cured with the ramp-cure mode. Group IV - specimens cured with single low intensity. Each group had two subgroups based on the composite resins used for making the specimen. The effectiveness of cure was determined from surface hardness values obtained from Rockwell hardness testing. A mathematical volumetric method was used to assess the volumetric shrinkage.
Results: Group III showed the best effectiveness of cure followed by group I and II. Group IV showed the least. Polymerization shrinkage was highest with group III and group II, were as was lowest for group I and IV. Charisma showed better effectiveness of cure and low polymerization shrinkage compared to Durafill VS.
Conclusion: This study emphasizes on the fact that, the soft-start polymerization modes (step curing and ramp curing) should be preferentially used over the conventional single (high or low light) intensities to cure composite resins, as its use results in optimal properties.
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http://dx.doi.org/10.4103/0972-0707.87205 | DOI Listing |
Oncol Res
January 2025
Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, India.
Background: To date, there is no effective cure for the highly malignant brain tumor glioblastoma (GBM). GBM is the most common, aggressive central nervous system tumor (CNS). It commonly originates in glial cells such as microglia, oligodendroglia, astrocytes, or subpopulations of cancer stem cells (CSCs).
View Article and Find Full Text PDFJ Adv Nurs
January 2025
Dipartimento Scienze Della Salute, Università degli Studi di Genova, Genova, Italy.
Aim(s): To adapt and validate the HSOPS 2 instrument for the Italian context and to describe the current patient safety culture amongst healthcare personnel working in Italian hospitals.
Design: Cross-sectional study.
Methods: We adapted and validated the HSOPS 2 instrument following the COSMIN guidelines: we performed a forward-backward translation, calculated the content validity index, evaluated face validity, acceptability (percentage of participants responding to all items on the questionnaire and to every specific item), construct validity (confirmatory factor analysis), and internal consistency (Cronbach's alpha for each dimension).
Acta Trop
January 2025
Klinikum Wuerzburg Mitte GmbH, Medical Mission Hospital, Department of Tropical Medicine, Würzburg, Germany.
Background: Regular mass drug administration of praziquantel has a positive impact on reducing the burden of human schistosomiasis, however transmission still persists in many areas. To reach disease elimination; tailored interventions are needed to not only further reduce infections but also to tackle areas of persistent high prevalences of infection. One proposed approach is timed treatment based on the natural disease transmission cycle in relation to seasons.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Biomedical Engineering, School of Life Science and Technology, Changchun University of Science and Technology, Changchun, 130022, China.
The cervical cell classification technique can determine the degree of cellular abnormality and pathological condition, which can help doctors to detect the risk of cervical cancer at an early stage and improve the cure and survival rates of cervical cancer patients. Addressing the issue of low accuracy in cervical cell classification, a deep convolutional neural network A2SDNet121 is proposed. A2SDNet121 takes DenseNet121 as the backbone network.
View Article and Find Full Text PDFGut
January 2025
Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK
Background: Low-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose ANd Titrated for Irritable bowel syndrome as Second-line treatment (ATLANTIS) trial.
Objective: To perform post hoc analyses of ATLANTIS for predictors of response to, and tolerability of, a TCA.
Design: ATLANTIS randomised 463 adults with IBS to amitriptyline (232) or placebo (231).
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