Immobilization-free screening of aptamers assisted by graphene oxide.

Chem Commun (Camb)

College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-713, South Korea.

Published: February 2012

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

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Source
http://dx.doi.org/10.1039/c2cc16473fDOI Listing

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