We summarize some aspects of electrostatic interactions in the context of viruses. A simplified but, within well defined limitations, reliable approach is used to derive expressions for electrostatic energies and the corresponding osmotic pressures in single-stranded RNA viruses and double-stranded DNA bacteriophages. The two types of viruses differ crucially in the spatial distribution of their genome charge which leads to essential differences in their free energies, depending on the capsid size and total charge in a quite different fashion. Differences in the free energies are trailed by the corresponding characteristics and variations in the osmotic pressure between the inside of the virus and the external bathing solution.
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Phys Rev Lett
December 2024
Stanford University, Department of Mechanical Engineering, Stanford, California 94305, USA.
The extreme electric fields created in high-intensity laser-plasma interactions could generate energetic ions far more compactly than traditional accelerators. Despite this promise, laser-plasma accelerator experiments have been limited to maximum ion energies of ∼100 MeV/nucleon. The central challenge is the low charge-to-mass ratio of ions, which has precluded one of the most successful approaches used for electrons: laser wakefield acceleration.
View Article and Find Full Text PDFAnalyst
January 2025
Jiangxi Provincial Key Laboratory of Organic Functional Molecules; Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China.
Glutathione (GSH) plays an important role in maintaining redox homeostasis in biological systems. Development of reliable glutathione sensors is of great significance to better understand the role of biomolecules in living cells and organisms. Based on the advantages of the photophysical properties of iridium complexes, we proposed a "turn-on" phosphorescent sensor.
View Article and Find Full Text PDFLangmuir
January 2025
Prof. Rashidi Laboratory of Organometallic Chemistry & Material Chemistry, Department of Chemistry, College of Science, Shiraz University, Shiraz, 7194684795, Iran.
In this study, a Pd nanoparticles@hydrogen-bonded organic framework (Pd NPs@HOF) thin film was fabricated at the toluene-water interface. The HOF was formed through the interaction of trimesic acid (TMA) and melamine (Mel) in the water phase, while Pd(0) was produced from the reduction of [PdCl(cod)] in the organic phase. The as-synthesized Pd NPs@HOF thin film was demonstrated to be an effective catalyst for the selective reduction of -nitrophenol and -nitrophenol to -aminophenol and -aminophenol.
View Article and Find Full Text PDFInt J Nanomedicine
January 2025
School of Basic Medicine, Ningxia Medical University, Yinchuan, People's Republic of China.
Background: Colorectal cancer (CRC) is a highly malignant and aggressive gastrointestinal tumor. Due to its weak immunogenicity and limited immune, cell infiltration lead to ineffective clinical outcomes. Therefore, to improve the current prophylaxis and treatment scheme, offering a favorable strategy efficient against CRC is urgently needed.
View Article and Find Full Text PDFNanoscale
January 2025
Physics Centre of Minho and Porto Universities (CF-UM-UP) and LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, 4710-057 Braga, Portugal.
Poly(vinylidene fluoride) (PVDF) is technologically relevant due to its thermal stability; chemical, mechanical and radiation resistance; transparency; biocompatibility; and ease of processing. Several of those applications are related to its high electroactivity, for which the β-phase of the polymer is its most renowned protagonist. In this context, extensive research has been conducted on the crystallization of PVDF in the β-phase, when processed from melt and from solution.
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