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Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1. | LitMetric
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Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1.

Naruhiko Sawa Pongtep Wilaipun Seisuke Kinoshita Takeshi Zendo Vichien Leelawatcharamas Jiro Nakayama Kenji Sonomoto

Appl Environ Microbiol

Laboratory of Microbial Technology, Division of Applied Molecular Microbiology and Biomass Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, Hakozaki, Higashi-ku, Fukuoka, Japan.

Published: February 2012

Enterococcus faecalis NKR-4-1 isolated from pla-ra produces a novel two-peptide lantibiotic, termed enterocin W, comprising Wα and Wβ. The structure of enterocin W exhibited similarity with that of plantaricin W. The two peptides acted synergistically, and their order of binding to the cell membrane was important for their inhibitory activity.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264125PMC
http://dx.doi.org/10.1128/AEM.06497-11DOI Listing

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