The case of a 68-year-old woman who had a big mass (plemorphic sarcoma) in the back of the neck and treated with surgical resection is presented. Primary malignant fibrous histiocytoma of the neck is rare, although it is among the most common soft tissue sarcomas in adults. The primary mode of therapy is surgery, but because of high rates of local and distant recurrence radiation, therapy should be added to decrease local relapse. Malignant fibrous histiocytoma is discussed with a brief literature review.
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http://dx.doi.org/10.1097/SCS.0b013e318231e281 | DOI Listing |
J Craniofac Surg
October 2024
Department of Pathology, Pathohistology and Medical Cytology, University Clinical Center of Serbia, Belgrade, Serbia.
Introduction: Sarcomas are relatively rare malignant tumors of mesenchymal origin, representing only about 1% of tumors in the head and neck region.
Materials And Methods: A retrospective study involved patients with sarcomas of the head and neck region who were diagnosed and treated over a 5-year period.
Results: Nine patients were included, 4 men and 5 women.
World J Clin Oncol
December 2024
Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Background: Primary squamous cell carcinoma (SCC) of the middle ear is rare, with non-keratinizing basaloid types being exceptionally uncommon. Distinguishing these cancers, often caused by viral factors (, human papillomavirus or Epstein-Barr virus), or specific genetic alterations (, bromodomain-containing protein 4-nuclear protein in or gene fused with FLI chromosomal rearrangement), from other cranial conditions, is difficult. The recently identified DEK::AFF2 non-keratinizing SCC (NKSCC) is a novel subtype, fitting the World Health Organization classification of head and neck neoplasms.
View Article and Find Full Text PDFJ Craniofac Surg
December 2024
Department of Neurosurgery, Weifang People's Hospital, Shandong Second Medical University, Weifang City, Shandong Province, China.
Malignant fibrous histiocytoma (MFH) is a malignancy originating from soft tissues and ranks among the most prevalent soft tissue sarcomas in adults. The considerable complexity and heterogeneity of MFH contribute to an obscure pathogenesis, presenting with atypical clinical manifestations and pathologic features that complicate the clinical diagnostic process. Typically, MFH manifests in the extremities, trunk, and retroperitoneum, while occurrences in the head and neck regions are exceedingly rare.
View Article and Find Full Text PDFHematol Oncol Clin North Am
December 2024
Department of Radiation Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA. Electronic address:
Heavy ion radiotherapy is an emerging technology for treating radioresistant solid tumors. Unlike current low-linear energy transfer techniques, heavy ion radiotherapy, such as carbon ion radiotherapy, enhances the biologic effects related to cancer therapy. Prospective clinical evidence has demonstrated feasibility and efficacy in several disease sites, including head and neck, thoracic, central nervous system, gastrointestinal, pelvic tumors, and sarcomas.
View Article and Find Full Text PDFZhonghua Er Ke Za Zhi
January 2025
Department of Medical Oncology, Pediatric Oncology Center,Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, National Key Clinical Discipline of Pediatric Oncology, Laboratory for Clinical Medicine, Capital Medical University, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing100045, China.
To analyze the clinical characteristics of children with head and neck rhabdomyosarcoma (RMS) and to summarize the mid-long term efficacy of Beijing Children's Hospital Rhabdomyosarcoma 2006 (BCH-RMS-2006) regimen and China Children's Cancer Group Rhabdomyosarcoma 2016 (CCCG-RMS-2016) regimen. A retrospective cohort study. Clinical data of 137 children with newly diagnosed head and neck RMS at Beijing Children's Hospital, Capital Medical University from March 2013 to December 2021 were collected.
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