AI Article Synopsis
- Stress negatively impacts mental health and bodily defenses, leading to diseases. Rasayana therapy, unlike conventional treatments, is effective in reducing stress and enhancing the body’s adaptability and mental endurance.
- The study evaluated the rasayana effect of Ranahamsa Rasayanaya (RR) using experimental models, including hypothermia and stress-induced gastric ulcers in rats.
- Results indicated that RR significantly reduced hypothermia and showed a non-significant decrease in gastric ulcers, supporting its adaptogenic and anti-stress properties as claimed by Sri Lankan traditional practitioners.
Article Abstract
Various types of stress not only harm the mental function, but also cause diseases by weakening body defenses. Rasayana therapy has an advantage over the conventional Kayachikitsa treatment in such conditions, as it is capable of counteracting the stress, promote the adaptogenic abilities of the body, enhance mental endurance, etc. These are the some of parameters for evaluation the rasayana effect of a drug, therefore the same have been studied to assess the rasayana effect of Ranahamsa Rasayanaya (RR). Experimental models such as forced swimming induced hypothermia and stress induced gastric ulcer formation have been carried out befitting on Charles Foster strain albino rats to determine the rasayana effect of RR. Statistically highly significant decrease in forced swimming induced hypothermia and non-significant decrease in gastric ulcer formation were observed in the treatment groups, when compared to the stress control group. These results show the probable adaptogenic and anti-stress activities of the test drug. The study results support the claims made by the Sri Lankan traditional practitioners that, the test drug is a potent rasayana formulation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215329 | PMC |
| http://dx.doi.org/10.4103/0974-8520.68201 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
47f: Bioadaptation to Low Doses of Xenobiotics in Aquaculture.
Biology (Basel)
November 2024
Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.
Agricultural and industrial activities are increasing pollution of water bodies with low doses of xenobiotics that have detrimental effects on aquaculture. The aim of this work was to determine the possibility of using 47f culture in fish aquaculture under the influence of low doses of xenobiotics as an adaptogen. An increase in the survival of individuals exposed to the xenobiotic bisphenol A solution and fed with the 47f was shown compared to control groups and, at the same time, the cytokine profile in the intestinal tissues of was also investigated.
View Article and Find Full Text PDFAshwagandha's Multifaceted Effects on Human Health: Impact on Vascular Endothelium, Inflammation, Lipid Metabolism, and Cardiovascular Outcomes-A Review.
Nutrients
July 2024
Department of Neonatology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, ul. Ujejskiego 75, 85-168 Bydgoszcz, Poland.
, commonly known as Ashwagandha, has been popular for many years. Numerous studies have shown that the extract of this plant, due to its wealth of active substances, can induce anti-inflammatory, neuroprotective, immunomodulatory, hepatoprotective, cardioprotective, anti-diabetic, adaptogenic, anti-arthritic, anti-stress, and antimicrobial effects. This review examines the impact of Ashwagandha extract on the vascular endothelium, inflammation, lipid metabolism, and cardiovascular outcomes.
View Article and Find Full Text PDFPhyto-therapeutic potential of Withania somnifera: Molecular mechanism and health implications.
Phytother Res
March 2024
Department of Biochemistry, School of Interdisciplinary and Applied Sciences, Central University of Haryana, Mahendergarh, India.
Withania somnifera, the plant named Indian ginseng, Ashwagandha, or winter cherry, has been used since ancient times to cure various health ailments. Withania somnifera is rich in constituents belonging to chemical classes like alkaloids, saponins, flavonoids, phenolic acids, and withanolides. Several chemotypes were identified based on their phytochemical composition and credited for their multiple bioactivities.
View Article and Find Full Text PDFModulation by of stress-induced anxiogenesis and airway inflammation in rats.
J Complement Integr Med
June 2024
Departments of Pharmacology, Hamdard Institute of Medical Sciences and Research (HIMSR), Jamia Hamdard, New Delhi, India.
Objectives: Stress is an aversive stimulus which disrupts the biological milieu of the organism and a variety of emotional and environmental stressors are known to influence allergic and immunological disorders like bronchial asthma but the pharmacological basis of such interactions is not clearly defined. (ashwagandha) is a potent anti-stress agent used widely in Indian traditional medicine and the present experimental study evaluated the effects of extract (WSE) on chronic stress-induced neurobehavioral and immunological responses in an experimental model of allergic asthma in rats.
Methods: Wistar rats (200-250 g) were immunized and challenged with ovalbumin (OVA) and exposed to restraint stress (RS) and WSE treatments for 15 days.
Effects of on Cortisol Levels in Stressed Human Subjects: A Systematic Review.
Nutrients
December 2023
Department of Biomedical and Clinical Sciences, University of Milano, 20157 Milan, Italy.
Background: Withania somnifera (WS), a popular medicinal plant of the Solanaceae family, contains active ingredients with antioxidant, anti-inflammatory, immunomodulatory, and anti-stress activities. However, its precise mechanisms of action and optimal use as a supplement are not yet fully understood. The objective of this systematic review is to assess the impact of WS supplementation on cortisol levels in stressed humans by analyzing clinical trials conducted prior to May 2023.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!