The currently available medications for the treatment of drug abuse have had only limited success. Anti-addiction vaccines, aimed at eliciting antibodies that block the pharmacological effects of drugs, have great potential for treating drug abuse. We review the status of two vaccines that are undergoing clinical trials (for cocaine and nicotine addiction) and two that are still in preclinical development (for methamphetamine and heroin addiction). We also outline the challenges and ethical concerns associated with the development of anti-addiction vaccines and their use as future therapeutics.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345810 | PMC |
| http://dx.doi.org/10.1038/clpt.2011.281 | DOI Listing |
Publication Analysis
Top Keywords
drug abuse
12
anti-addiction vaccines
8
vaccines
4
vaccines drug
4
abuse currently
4
currently medications
4
medications treatment
4
treatment drug
4
abuse limited
4
limited success
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!