One hundred consecutive patients, who underwent bronchoscopic examination for diagnostic purposes, were studied with regard to various aspects of possible SaO2 deterioration. Relevant findings are as follows: (1) The pulse oximeter is as good as the conventional blood gas analyser for quantitating SaO2; (2) oxygen desaturation in the range of 1 to 25 per cent (median 5, mean 5.6 +/- 4) occurred in approximately 97 per cent of the bronchoscopy examinees; recuperation time of SaO2 was 1 to 34 minutes (median 6, mean 8.2 +/- 6.5); (3) the factor aggravating desaturation included the examination of patients in the sitting position; the fact that bronchial washing was connected with greater SaO2 deterioration in the non-hypoxaemic group of patients needs further investigation with regard to its role in the mechanism of oxygen desaturation; (4) the amount of fluid instilled intra-tracheally, bronchial biopsy and duration of the procedure were not related to the decline in SaO2. Based on the results of the present study, the authors suggest that all procedures ought to be performed on patients undergoing examination in the supine position, and that the patients should be supplemented with low-flow oxygen.
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Nat Sci Sleep
January 2025
Sleep Center, Department of Geriatric Respiratory, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People's Republic of China.
Purpose: Approximately 30% of patients with sleep-disordered breathing (SDB) present with masked hypertension, primarily characterized by elevated nighttime blood pressure. This study aimed to develop a hypertension prediction model tailored for primary care physicians, utilizing simple, readily available predictors derived from type IV sleep monitoring devices.
Patients And Methods: Participants were recruited from communities in Guangdong Province, China, between April and May 2021.
BMC Anesthesiol
January 2025
Department of Anesthesiology and Reanimation, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey.
Background: Patient safety is important in daily anesthesia practices, and providing deep anesthesia is difficult. Current debates on the optimal anesthetic agents highlight the need for safer alternatives. This study was justified by the need for safer and more effective anesthetic protocols for outpatient hysteroscopic procedures, particularly those conducted outside the operating room.
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January 2025
Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Obstructive sleep apnea (OSA) patients have varying degrees of cognitive impairment, but the specific pathogenic mechanism is still unclear. Meanwhile, poor compliance with continuous positive airway pressure (CPAP) in OSA prompts better solutions. This study aimed to identify differentially expressed genes between the non-obese OSA patients and healthy controls, and to explore potential biomarkers associated with cognitive impairment.
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January 2025
Institut des Neurosciences Cellulaires et Intégratives, CNRS UPR 3212 / Université de Strasbourg, Strasbourg, France; CHU Strasbourg, Médecine et Réanimation du nouveau-né, Service de Pédiatrie 2, Pôle médico chirurgical Pédiatrique de Hautepierre, Avenue Molière, 67091 Strasbourg, FR, France.
Background: Care procedures for preterm infants can induce stress that may disrupt homeostasis, possibly altering cerebral perfusion or oxygenation. We evaluated the physiological and cerebral oxygenation changes during the routine care of very preterm infants.
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J Sleep Res
January 2025
Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
As available treatments in obstructive sleep apnea are all associated with side-effects or adherence problems, there is a need for alternative treatment options. In this randomized, open, parallel-group intervention study, the effect of head extension by cervical collar was evaluated in patients with moderate obstructive sleep apnea. One-hundred patients with moderate obstructive sleep apnea (apneas and hypopneas per estimated hours asleep = respiratory events index: 15-30) were randomized to either lifestyle intervention, or cervical collar in combination with lifestyle intervention.
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