Brain abscess caused by Nocardia is a relatively rare disease, but its prognosis is poor, with the fatality being 3 times as high as that of other types of brain abscess. Nocardiosis caused by N. farcinica has higher fatality rates than nocardiosis caused by the other bacteria of the genus Nocardia. We report two cases of brain abscess caused by N. farcinica. Case 1: 72-year-old immunocompetent man. In this case, the disease healed in response to burr hole drainage and treatment with antibiotics (pazufloxacin, ciprofloxacin). Case 2: A 78-year-old woman with a history of liver cirrhosis. This patient received burr hole drainage and treatment with multiple antibiotics (sulfamethoxazole/trimethoprim, pazufloxacin, meropenem, amikacin, minocycline, and linezolid). Her brain abscess tended to alleviate but her general condition worsened, leading to death. N. farcinica is often resistant to multiple antibiotics. For treatment of brain abscess caused by this bacterium, it is essential to perform pathogen identification and a drug sensitivity test immediately, and to select optimum antibiotics, taking into account the general condition of individual patients.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Concurrent Onset of Osimertinib-Induced Heart Failure and Metronidazole-Induced Encephalopathy During Brain Abscess Treatment: A Report of a Rare Case.
Cureus
December 2024
Respiratory Medicine, Saitama Medical University International Medical Center, Hidaka, JPN.
We report a rare case of concurrent onset of osimertinib-induced heart failure and metronidazole-induced encephalopathy during treatment of a brain abscess. A 78-year-old female with lung adenocarcinoma presented with neurological symptoms and was diagnosed with a brain abscess. During treatment, she developed heart failure and encephalopathy, linked to osimertinib and metronidazole, respectively.
View Article and Find Full Text PDFA rare presentation: Brain abscess secondary to urinary tract infection.
Radiol Case Rep
March 2025
Internal Medicine Department, ULS do Alto Ave - Hospital Senhora da Oliveira Guimarães, Rua dos Cutileiros, n114, Creixomil, 4835-044, Portugal.
Cerebral abscess due to hematogenous spread originating from a urinary infection is a rare condition. This clinical case involves an 80-year-old woman with a history of recurrent urinary infections. She presented to the emergency department with fever and altered consciousness.
View Article and Find Full Text PDFCerebral cavernous malformation with associated Streptococcus pyogenes abscess in a child: a case report and literature review.
Childs Nerv Syst
December 2024
Department of Neurosurgery, Sheffield Children's Hospital, Sheffield, UK.
Cerebral cavernous malformations (CCMs) are angiographically occult vascular lesions that present with a variety of neurological symptoms, including seizures, features of raised intracranial pressure and focal neurological deficits. In extremely rare circumstances, CCMs have presented with concomitant brain abscess formation. To date, five cases have previously been reported, the majority of which have affected patients aged 16 years or older.
View Article and Find Full Text PDFDiagnostic role of sonography in early detection and surgical intervention of an epidural abscess: A case report.
Australas J Ultrasound Med
November 2024
Argentinian Critical Care Ultrasonography Association (ASARUC) Buenos Aires C1424FSD Argentina.
Introduction: Intracranial epidural abscesses require swift diagnosis and treatment. While magnetic resonance imaging (MRI) is preferred for its detailed visualisation, it is costly and time-consuming. Transcranial sonography offers a rapid, portable and cost-effective alternative for assessing brain lesions.
View Article and Find Full Text PDFClinical features and outcome of brain abscess after introduction of CT and MRI: A meta-analysis.
J Infect
December 2024
European Society of Clinical Microbiology and Infectious Diseases, Study Group for Infections of the Brain (ESGIB), Basel, Switzerland; Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Objective: To describe the clinical features and outcome of brain abscess since introduction of computerized tomography and magnetic resonance imaging.
Methods: MEDLINE and Embase were searched using "brain abscess" or "cerebral abscess" from 1970 through 2023 and analyses restricted to study populations hospitalized after 1980. Single-variable meta-analyses were done using a random-effects model.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!