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Determinants of fertility in timed artificial insemination programs in beef cattle: predictive ability and risk factors from almost 2 million data points.
Animal
December 2024
Alta Genetics Brasil Ltda., Uberaba 38055-010, Brazil.
Timed artificial insemination (TAI) is a technology widely used in cattle production based on controlling ovarian follicular growth. This study analyzed a large database aiming to determine the influence of several intrinsic and extrinsic female factors, as well as their interactions to determine risk factors and produce prediction ability in beef cattle. A total of 1 832 999 TAIs conducted on 2 002 farms across South American countries were considered for the analysis, including 15 main fixed effects or interactions in the statistical model, in addition to five random effects.
View Article and Find Full Text PDFIs there an impact of surgeon's experience on in-hospital outcome in patients with operatively treated proximal humerus and humerus shaft fractures?
Surg Pract Sci
March 2025
Division of Trauma Surgery, University Hospital Zurich (USZ), University of Zurich (UZH), Raemistrasse 100, 8091 Zuerich, Switzerland.
Background: Proximal humerus and shaft fractures are common, comprising 10-11 % of all fractures. Progress in their management includes refined surgical techniques and implants, coupled with a deeper understanding of fracture patterns.
Aims: This study examines the effect of surgical education on in-hospital outcomes for operatively treated proximal and humerus shaft fractures, aiming to enhance patient care and results.
Genomics yields biological and phenotypic insights into bipolar disorder.
Nature
January 2025
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants of European, East Asian, African American and Latino ancestries (n = 158,036 cases with bipolar disorder, 2.
View Article and Find Full Text PDFCharacterizing the diabetes-induced pathological changes of the mouse lung by single-cell RNA sequencing.
Life Sci
January 2025
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shiquan 1(st) Rd., Sanmin Dist., Kaohsiung City 807378, Taiwan; Drug Development and Value Creation Research Center, Kaohsiung Medical University, No. 100, Shiquan 1(st) Rd., Sanmin Dist., Kaohsiung 807378, Taiwan; National Pingtung University of Science and Technology, Department of Biological Science and Technology, No. 1, Shuefu Road, Neipu, Pingtung 912301, Taiwan. Electronic address:
Pulmonary disorders are exacerbated by high blood sugar, leading to a disordered immune defense and increased susceptibility to infection. Type 2 diabetes mellitus (T2D) is characterized by insulin resistance and inadequate insulin production. Mechanisms leading to pulmonary alternation due to T2D are not clear.
View Article and Find Full Text PDFAn alternative fixation for all mild and moderate hallux valgus cases enabling intraoperative readjustment.
J Orthop Surg Res
January 2025
Department of Orthopaedics and Traumatology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey.
Background: The development of a cost-effective and easily applicable fixation method to address all components of hallux valgus (HV) surgery is of great importance to the field. This study aims to assess the clinical efficacy of an alternative fixation method that combines the advantages aspects of commonly used distal osteotomy techniques and evaluate its level of applicability in the treatment of mild and moderate HV cases.
Methods: The retrospectively designed study was conducted at Adana City Training and Research Hospital, Adana, Türkiye.
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