Objective: Calcifying fibrous tumor is a rare, benign soft-tissue tumor of unknown etiology, characterized by hyalinized collagenous fibrous tissue with psammomatous or dystrophic calcification and focal lymphoplasmacytic infiltrate known to involve different organ systems. Involvement of the spine and the presence of metaplastic ossification previously have not been reported.
Intervention: We report a 44-year-old female with progressive nontraumatic flank pain. Imaging revealed a left-sided retroperitoneal calcified mass attached to L5 body with no evidence of extension into the neural foramina, nearby vascular structures, or psoas muscle. The patient had an en bloc resection of the tumor via the transabdominal approach. A pathologic diagnosis of calcifying fibrosis with metaplastic ossification of the spine was reported. Postoperative recovery was uneventful and there is no recurrence after 18 months of follow-up.
Conclusion: Calcifying fibrous tumor, a rare benign soft tissue tumor must be considered in the differential diagnosis of a retroperitoneal calcified mass closely associated with the spinal column. Spine surgeons should be aware of this rare pathologic disease entity and although its natural history is not clear, marginal excision is usually adequate.
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http://dx.doi.org/10.1016/j.wneu.2011.04.022 | DOI Listing |
Photodiagnosis Photodyn Ther
January 2025
Department of Cardiology, Shanghai East Hospital of Clinical Medical College, Nanjing Medical University, Nanjing 211166, China; Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address:
Background: Atherosclerosis is a lipid-driven, systemic immune-inflammatory disease characterized by the accumulation of plaque within the arterial walls. Plaque regression can occur following appropriate treatment interventions. Optical coherence tomography (OCT), a high-resolution imaging modality, is frequently employed to assess plaque morphology.
View Article and Find Full Text PDFSci Rep
January 2025
Medical Physics, University of Wisconsin School of Medicine and Public Health (UW-SMPH), Madison, USA.
Carotid plaques-the buildup of cholesterol, calcium, cellular debris, and fibrous tissues in carotid arteries-can rupture, release microemboli into the cerebral vasculature and cause strokes. The likelihood of a plaque rupturing is thought to be associated with its composition (i.e.
View Article and Find Full Text PDFKardiol Pol
January 2025
Department of Coronary and Structural Heart Diseases, National Institute of Cardiology, Warszawa, Poland.
Background: Preliminary research indicates that higher iron levels are associated with worse outcomes in patients with coronary artery disease.
Aims: The study aimed to investigate the relationship between iron levels and the type and composition of coronary plaques.
Methods: In patients with ≥1 coronary stenosis ≥50% on computed tomography angiography, iron levels, presence of high-risk plaque features, such as low-attenuation plaque (LAP), napkin-ring sign, positive remodeling, and spotty calcium, as well as type and plaque composition (calcified/fibrous/fibro-fatty/necrotic core) were evaluated.
Cureus
November 2024
Radiodiagnosis, Sawai Man Singh (SMS) Medical College and Hospital, Jaipur, IND.
Background: Stroke is a leading cause of death and disability worldwide, affecting millions annually. Accurate etiological diagnosis is critical for the effective treatment and prevention of recurrent strokes. Traditional luminal imaging techniques like computed tomography (CT) and magnetic resonance angiography (MRA) provide limited information, focusing solely on vessel lumen characteristics.
View Article and Find Full Text PDFUltrasound Med Biol
February 2025
Department of Medical Imaging, Medical UltraSound Imaging Center, Radboud University Medical Center, Nijmegen, The Netherlands; Physics of Fluids Group, University of Twente, Meander (27), Enschede, The Netherlands. Electronic address:
Objective: The rupture of vulnerable plaques in the carotid artery is a leading cause of strokes. While magnetic resonance imaging (MRI) is the standard for quantifying plaque composition, its high costs and lengthy procedure times limit large-scale use. Compound ultrasound strain imaging (CUSI) ultrasound offers a non-invasively alternative by assessing tissue deformation/strain within the arterial wall.
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