Event structure describes the relationships between general semantics (Aktionsart) of the verb and its syntactic properties, separating verbs into two classes: telic verbs, which denote change of state events with an inherent end-point or boundary (catch, rescue), and atelic, which refer to homogenous activities (tease, host). As telic verbs describe events, in which the internal argument (Patient) is affected, we hypothesized that processing of telic verb template would activate syntactic position of the Patient during sentence comprehension. Event-related brain potentials (ERPs) were recorded from 20 English speakers, who read sentences with reduced Object relative clauses, in which the verb was either telic or atelic. ERPs in relative clauses diverged on the definite article preceding the Agent: the atelic condition was characterized by larger amplitude negativity at the N100. Such processing differences are explained by activation of the syntactic position for the Patient by the event structure template of telic verbs.
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Genome Res
January 2025
Biodiversity Research Center, Academia Sinica, Taipei 115, Taiwan;
Groups of orthologous genes are commonly found together on the same chromosome over vast evolutionary distances. This extensive physical gene linkage, known as macrosynteny, is seen between bilaterian phyla as divergent as Chordata, Echinodermata, Mollusca, and Nemertea. Here, we report a unique pattern of genome evolution in Bryozoa, an understudied phylum of colonial invertebrates.
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Sunita Sanghi Centre of Aging and Neurodegenerative Diseases (SCAN), Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Aggregation of α-synuclein (α-Syn) and Lewy body (LB) formation are the key pathological events implicated in Parkinson's disease (PD) that spread in a prion-like manner. However, biophysical and structural characteristics of toxic α-Syn species and molecular events that drive early events in the propagation of α-Syn amyloids in a prion-like manner remain elusive. We used a neuronal cell model to demonstrate the size-dependent native biological activities of α-Syn fibril seeds.
View Article and Find Full Text PDFSci Rep
January 2025
Nanyang Technological University, Singapore, 639798, Singapore.
Although electric vehicles supplied through distributed generators (DGs) have been universally researched to reduce CO emissions, the accurate current sharing regarding islanded multi-bus DC charging stations considering three charging modes of electric vehicles, i.e., constant current mode, constant power mode and constant voltage mode, is rarely realized.
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January 2025
Departamento de Química, Universidade Federal do Paraná, 81531-980, Curitiba-PR, Brasil.
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January 2025
Institut de Recherche en Santé, Environnement et Travail (Irset)─Inserm─EHESP, UMR_S 1085, Université de Rennes, 9 av. du Professeur Léon Bernard, F-35042 Rennes, France.
Amyloidosis is a group of proteinopathies characterized by the systemic or organ-specific deposition of proteins in the form of amyloid fibers. Nearly 40 proteins play a role in these pathologies, and the structures of the associated fibers are beginning to be determined by Cryo-EM. However, the molecular events underlying the process, such as fiber nucleation and elongation, are poorly understood, which impairs developing efficient therapies.
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