The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder transitional cell carcinoma) were evaluated, and discussed in terms of structure-activity relationship.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ejmech.2011.11.005 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!