The possibility of using modified peroxyredoxins as powerful antioxidant agents has been considered. Peroxyredoxins immobilized on perfluorocarbon emulsions and PTD-modified peroxyredoxins have been studied. It has been shown that peroxyredoxins efficiently bind to particles of perfluorocarbon emulsions, while maintaining their antioxidant properties. A panel of PTD-modified peroxyredoxins has been created and peroxyredoxins most effective both in antioxidant properties and the ability to penetrate cells have been selected. The modified peroxyredoxins obtained may serve as the basis for the design of drug with powerful antioxidant action.

Download full-text PDF

Source

Publication Analysis

Top Keywords

modified peroxyredoxins
8
powerful antioxidant
8
perfluorocarbon emulsions
8
ptd-modified peroxyredoxins
8
antioxidant properties
8
peroxyredoxins
7
[modified peroxiredoxins
4
peroxiredoxins prototypes
4
prototypes drugs
4
drugs powerful
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!