The infection of the root canal system is considered to be a polymicrobial infection, consisting of both aerobic and anaerobic bacteria. Because of the complexity of the root canal infection, it is unlikely that any single antibiotic could result in effective sterilization of the canal. A combination of antibiotic drugs (metronidazole, ciprofloxacin, and minocycline) is used to eliminate target bacteria, which are possible sources of endodontic lesions. Three case reports describe the nonsurgical endodontic treatment of teeth with large periradicular lesions. A triple antibiotic paste was used for 3 months. After 3 months, teeth were asymptomatic and were obturated. The follow-up radiograph of all the three cases showed progressive healing of periradicular lesions. The results of these cases show that when most commonly used medicaments fail in eliminating the symptoms then a triple antibiotic paste can be used clinically in the treatment of teeth with large periradicular lesions.
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http://dx.doi.org/10.4103/0976-237X.62510 | DOI Listing |
Diagn Microbiol Infect Dis
December 2024
Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; Department of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia; Department of Prosthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Int J Clin Pediatr Dent
October 2024
Department of Endodontics, Galilee College of Dental Sciences, Nahariya; Azrieli Faculty of Medicine, Bar-Ilan University, Ramat Gan, Israel.
Unlabelled: Regenerative endodontic treatment (RET) has been suggested for the treatment of traumatized necrotic immature teeth. There are only a few reports of using RET to treat a horizontal root fracture. The aim of this paper is to describe successful regenerative retreatment in a tooth with a horizontal root fracture and dens invaginatus.
View Article and Find Full Text PDFClin Oral Investig
November 2024
Department of Medical Biochemistry Department, Health Sciences University Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Objectives: This study aimed to explore whether using sonic irrigant activation during endodontic treatment favors periradicular repair in teeth with apical periodontitis.
Materials & Methods: One clinician treated 140 posterior (either premolar or molar) asymptomatic teeth with periapical lesions: 70 were randomly assigned to the sonic activation with EndoActivator (EA) group, and 70 were treated by conventional needle irrigation (CNI). Both groups underwent chemomechanical root canal preparation using 35/04 diameter rotary files and 2.
Eur Endod J
December 2024
Faculty of Dentistry, Cairo University, Cairo, Egypt.
Objective: The purpose of this randomized, controlled study was to evaluate the effectiveness of Biodentine compared with MTA used as a pulp space barrier in healing periapical lesions and regaining pulp sensitivity after regenerative treatment in mature single-canal permanent teeth with pulp necrosis and apical periodontitis.
Methods: The study involved 36 patients with mature teeth with necrotic pulp and apical periodontitis. The patient underwent a regenerative treatment that utilized the blood clot technique.
Rev Cient Odontol (Lima)
September 2024
Departamento de Estomatoquirúrgica, Facultad de Odontología, Universidad de Carabobo. Valencia, Venezuela. , Universidad de Carabobo Departamento de Estomatoquirúrgica Facultad de Odontología Universidad de Carabobo Valencia Venezuela
Introduction: Non-surgical endodontic treatment aims to prevent apical periodontitis, achieved with the disinfection of the root canal system. Additionally, there are pathologies where the toxic content of the canal goes to the periradicular tissues, causing osteolysis or lesions of the bone tissue that are radiographically observed as radiolucent images. When the endodontic treatment is successful, the repair of these lesions occurs over time.
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