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Quality assessment of clinical guidelines in the care of laryngitis and pharyngitis according to AGREE II.
Codas
January 2025
Departamento de Farmácia, Universidade de Brasília - UnB - Brasília (DF), Brasil.
Purpose: The study aimed to identify and assess the methodological quality of essential clinical guidelines for the management of laryngitis and pharyngitis.
Methods: A systematic search of clinical guidelines for the management of laryngitis and pharyngitis was performed in three databases. Methodological quality was assessed according to AGREE II, in which each item in its domains was scored by four independent evaluators.
Perturbation of peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.
mBio
January 2025
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
Unlabelled: Peptidoglycan (PG) is an important bacterial macromolecule that confers cell shape and structural integrity, and is a key antibiotic target. Its synthesis and turnover are carefully coordinated with other cellular processes and pathways. Despite established connections between the biosynthesis of PG and the outer membrane, or PG and DNA replication, links between PG and folate metabolism remain comparatively unexplored.
View Article and Find Full Text PDFVopX, a novel T3SS effector, modulates host actin dynamics.
mBio
January 2025
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA.
Unlabelled: Pathogenic strains cause cholera using different mechanisms. O1 and O139 serogroup strains use the toxin-co-regulated pilus (TCP) and cholera toxin (CT) for intestinal colonization and to promote secretory diarrhea, while non-O1/non-O139 serogroup strains are typically non-toxigenic and use alternate virulence factors to cause a clinically similar disease. An O39 serogroup, TCP/CT-negative strain, named AM-19226, uses a type III secretion system (T3SS) to translocate more than 10 effector proteins into the host cell cytosol.
View Article and Find Full Text PDFFirst Report of Causing Bacterial Leaf and Panicle Blight of Rice in Louisiana, USA.
Plant Dis
January 2025
LSU AgCenter, Plant Pathology and Crop Physiology, Baton Rouge, Louisiana, United States.
In July 2023, panicle and leaf blight-like symptoms were observed from the rice () variety, PVL03, in research field plots in Louisiana (Rayne, LA 70578, USA; 30.21330⁰ N, 92.37309⁰ W).
View Article and Find Full Text PDFgen. nov., sp. nov.: a novel species of a novel genus in the family , isolated from the sediment of a tidal flat located in Zhoushan, China.
Int J Syst Evol Microbiol
January 2025
College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, PR China.
A Gram-stain-negative, aerobic and rod-shaped bacterium, designated as HZG-20, was isolated from a tidal flat in Zhoushan, Zhejiang Province, China. The 16S rRNA sequence similarities between strain HZG-20 and RR4-56, NNCM2, P31 and X9-2-2 were 98.9, 91.
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