Interaction of a frequency-chirped laser pulse with single protons and a hydrogen gas target is studied analytically and by means of particle-in-cell simulations, respectively. The feasibility of generating ultraintense (10(7) particles per bunch) and phase-space collimated beams of protons (energy spread of about 1%) is demonstrated. Phase synchronization of the protons and the laser field, guaranteed by the appropriate chirping of the laser pulse, allows the particles to gain sufficient kinetic energy (around 250 MeV) required for such applications as hadron cancer therapy, from state-of-the-art laser systems of intensities of the order of 10(21) W/cm(2).
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http://dx.doi.org/10.1103/PhysRevLett.107.185002 | DOI Listing |
Nanomaterials (Basel)
February 2025
National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba 305-8568, Japan.
Ultrafast laser processing is a critical technology for micro- and nano-fabrication due to its ability to minimize heat-affected zones. The effects of intensity variation on the ultrafast laser ablation of fused silica were investigated to gain fundamental insights into the dynamic modulation of pulse intensity. This study revealed significant enhancement in ablation efficiency for downward ramp intensity modulation compared to the upward ramp.
View Article and Find Full Text PDFNanomaterials (Basel)
February 2025
Faculty of Engineering, Tokyo University of Agriculture and Technology, 2-24-16, Nakacho, Koganei 184-8588, Tokyo, Japan.
We report on the formation of homogeneous nanostructures using a two-step ablation process with square flattop beams of femtosecond (fs) laser pulses. The Gaussian beam output from a ytterbium fs laser system was converted to a square flattop beam by a refractive beam shaper and a square mask. This beam was split into two with a diffraction optical element, and then the downsized beams were spatially and temporally superimposed on a titanium surface.
View Article and Find Full Text PDFOpen Forum Infect Dis
December 2024
Institute for Infection and Immunity, St George's University of London, London, UK.
Background: Every year an estimated 2-3 million babies are stillborn, with a high burden in Africa. Infection is an important driver of stillbirth. There is a lack of data on the bacterial causes of stillbirth in Uganda, contributing to a lack of interventions such as effective prophylaxis and development of maternal vaccine options against the most implicated pathogens.
View Article and Find Full Text PDFNanoscale
March 2025
Departamento de Química Física, Universidad Complutense de Madrid, 28040 Madrid, Spain.
The combination of different metals into a discrete colloidal nanocrystal (NC) lattice to form solid solutions can result in synergetic and non-additive effects, leading to physicochemical properties distinct from those observed in monometallic NCs. However, these features are influenced by parameters that are challenging to control simultaneously using conventional synthesis methods, including composition, morphology, size, and elemental distribution. In this study, we present a methodology that exploits seed-mediated growth routes and pulsed laser-induced ultrafast heating to synthesize bimetallic and trimetallic colloidal alloy NCs with tailored compositions, well-defined spherical morphologies, and precise control over the number of atoms per NC lattice.
View Article and Find Full Text PDFAnal Chem
March 2025
Department of Chemistry, Atomic and Mass Spectrometry - A&MS Research Group, Ghent University, Campus Sterre, Krijgslaan 281-S12, Ghent 9000, Belgium.
Novel low-dispersion ablation cell designs and highly efficient aerosol transport systems have enabled fast elemental mapping using laser ablation-ICP-mass spectrometry (LA-ICP-MS) at high spatial resolution and its application in various research fields. Nowadays, the fastest low-dispersion setups enable narrow single pulse responses (SPR, duration of the transient signal observed upon a single laser shot), which enhance the signal-to-noise ratio and boost the pixel acquisition rate attainable in elemental mapping applications. In this work, the analytical performance of a nanosecond 193 nm ArF* excimer-based kHz laser in combination with a low-dispersion tube-type ablation cell, coupled to an ICP-mass spectrometer equipped with a time-of-flight (ToF) analyzer, was evaluated.
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