We study biological evolution in a high-dimensional genotype space in the regime of rare mutations and strong selection. The population performs an uphill walk which terminates at local fitness maxima. Assigning fitness randomly to genotypes, we show that the mean walk length is logarithmic in the number of initially available beneficial mutations, with a prefactor determined by the tail of the fitness distribution. This result is derived analytically in a simplified setting where the mutational neighborhood is fixed during the adaptive process, and confirmed by numerical simulations.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/PhysRevLett.107.178102 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Effects of Commando Training on Stress, Cognitive Performance, and Group Behavior in Military Personnel: An Exploratory Study.
Mil Med
March 2025
Essonne, French Military Biomedical Research, IRBA, Brétigny-sur-Orge 91220, France.
Background: Military personnel are exposed to a high level of operational stress that degrades their psychophysiological and cognitive performance and could impact the mission. Commando training is a unique opportunity to assess psychological, physiological, and cognitive performance in an ecological setting.
Methods: Psychological, physiological, and cognitive performance were evaluated at baseline, and before and after a 1-week commando training course consisting of exercises and night walks.
Perceptions About Dyadic Physical Activity Intervention for Rural-Dwelling People With Cognitive Impairment.
J Aging Phys Act
March 2025
Social and Behavioral Sciences, Yale School of Public Health, Yale University, New Haven, CT, USA.
Background/objectives: Rural populations face an elevated risk of Alzheimer's disease and related dementias partially attributed to modifiable risk factors such as physical inactivity. The study gathered key community partners' perspectives about (a) feasibility of implementing the telerehabilitation physical activity behavioral (TPAB) intervention, a virtual program aimed at increasing daily stepping with sensor-based monitoring, and (b) necessary adaptions for implementation for rural-dwelling people with cognitive impairment and care partners (dyads).
Methods: Eleven rural-dwelling individuals (three medical providers, four older adults, and four care partners of individuals with mild cognitive impairment) in Nebraska were recruited for a focus group via fliers and word of mouth.
Sagittal Plane Kinematic Deviations and Spatio-Temporal Gait Characteristics in Children with Idiopathic Toe Walking: A Comparative Analysis Using Statistical Parametric Mapping.
Diagnostics (Basel)
February 2025
Department of Physical Education & Sports, University of Granada, 18071 Granada, Spain.
: Idiopathic Toe Walking (ITW) is a pediatric gait disorder characterized by persistent toe-to-heel ambulation in the absence of neurological, orthopedic, or developmental abnormalities. While spatio-temporal parameters often remain within normal ranges, subtle but clinically significant kinematic deviations may underlie compensatory mechanisms that sustain gait functionality. This study aims to evaluate spatio-temporal and sagittal plane kinematic differences between children with ITW and typically developing peers using Statistical Parametric Mapping (SPM).
View Article and Find Full Text PDFConceptual Metaphors About Voice in the Teacher-Student Interaction System During Western Classical Singing Lessons.
J Voice
March 2025
Facultad de Ciencias de la Educación, Universidad San Sebastián, Concepción, Chile.
Objectives: This study explores the use of conceptual metaphors (CM) by teachers during Western classical singing lessons to facilitate communication and improve students' understanding of vocal technique. It examines the role of metaphors in enhancing the interaction between teachers and students within a cognitive linguistics framework.
Study Design: Cross-sectional, interpretative study.
Embodied design for enhanced flipper-based locomotion in complex terrains.
Sci Rep
March 2025
Department of Electrical Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Robots are becoming increasingly essential for traversing complex environments such as disaster areas, extraterrestrial terrains, and marine environments. Yet, their potential is often limited by mobility and adaptability constraints. In nature, various animals have evolved finely tuned designs and anatomical features that enable efficient locomotion in diverse environments.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!