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COMPARISON OF DENTIN HYPERSENSITIVITY MANAGEMENT OF EXPOSED ROOT SURFACES BY DENTIN BONDING AGENT AND THINLY APPLIED GLASS IONOMER CEMENT: A CLINICAL TRIAL.
J Ayub Med Coll Abbottabad
December 2024
Department of Prosthodontics, Akhtar Saeed Medical and Dental College, Lahore. -Pakistan.
Article Synopsis
- Dentin hypersensitivity is a prevalent dental issue, likened to the common cold in its frequency, prompting a study comparing the effectiveness of glass ionomer cement and dentin bonding agents in managing this condition in patients at Peshawar Dental College.
- A quasi-experimental study involving 60 patients aged 18-70 was conducted, splitting them into two groups: one treated with glass ionomer cement and the other with dentin bonding agent. Sensitivity levels were measured before and after treatment using a visual analogue scale.
- Results showed that pain levels decreased significantly immediately after treatment for both groups; however, follow-ups at 1 week and 6 weeks revealed no notable differences in effectiveness, with most patients reporting mild pain in both treatment groups
[Clinical Management of Respiratory Diseases in Neurosurgical Settings].
No Shinkei Geka
November 2024
Department of Pulmonology, Yokohama City University Graduate School of Medicine.
Respiratory diseases, such as chronic obstructive pulmonary disease(COPD)and asthma, are becoming increasingly prevalent in super-aging societies. In Japan, the estimated prevalence of COPD among individuals aged 40 years and above is 8.6%, while asthma affects about 10% of adults.
View Article and Find Full Text PDFThe effects of chronic neuropathic pain on the self-administration of highly potent MOR agonist, fentanyl.
bioRxiv
November 2024
Department of Pharmacology, University of Michigan, Ann Arbor Michigan, 48109.
There is significant overlap between chronic pain and opioid use disorder (OUD) patient populations such that approximately 50-65% of chronic pain patients have OUD. However, we understand relatively little about how chronic, long-lasting pain states alter ongoing self-administration of opioid analgesics. Thus, the goal of this study was to determine if chronic neuropathic pain altered the ongoing self-administration of fentanyl, or a non-opioid drug of abuse, cocaine.
View Article and Find Full Text PDFPotential therapeutic uses of L-citrulline beyond genetic urea cycle disorders.
J Inherit Metab Dis
November 2024
George Washington University, Maryland, USA.
Article Synopsis
- L-citrulline, a non-essential amino acid involved in the urea cycle, is primarily known for its role in managing genetic urea cycle disorders, but recent studies reveal its potential in treating conditions linked to nitric oxide deficiency and oxidative stress.
- Citrulline may have beneficial effects in several medical conditions such as sickle cell disease, post-operative pulmonary hypertension, hepatic veno-occlusive disease, and bronchopulmonary dysplasia, by enhancing nitric oxide production and improving vascular health.
- While promising results suggest citrulline could serve as an adjunct therapy in these conditions, more research is needed to establish proper dosing and long-term safety and effectiveness.
Comparative evaluation of desensitizing agents on shear bond strength of zirconia to dentin.
BMC Oral Health
November 2024
Ege University Faculty of Dentistry Department of Prosthodontics, İzmir, Turkey.
Background: The purpose of the study is to evaluate the effect of 7 different desensitizing agents on the shear bond strength (SBS) of zirconia restorations to dentin with a self-adhesive resin cement and determine the failure modes.
Methods: Eighty molars' occlusal surfaces were ground to expose dentin and were randomly divided into 8 groups (n = 10): 1. Gluma (HEMA/Glutaraldehyde) 2.
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