Enhanced reduction of C-N multiple bonds using sodium borohydride and an amorphous nickel catalyst.

Org Biomol Chem

State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug, Hebei University of Science & Technology, Shijiazhuang, 050018, People's Republic of China.

Published: January 2012

Amorphous nickel powder (Ni(0)) was utilised as a catalyst under mild, aqueous, basic conditions for enhancing the sodium borohydride-mediated reduction of C-N multiple bonds such as oximes, imines, hydrazones and nitriles to produce the corresponding amines in good to excellent yields.

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Source
http://dx.doi.org/10.1039/c1ob06471aDOI Listing

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