A series of resorcinaren-PAMAM dendrimers with benzodiazepines in the periphery were synthesized and their anticancer properties studied. The synthesized dendrimers showed potential anticancer activities, which were enhanced in the presence of a chloro-substituent in the second ring of the 5-aryl-1,4-benzodiazepine. The dendrimers were characterized by IR, (1)H and (13)C NMR, UV-vis absorption, electrospray (ES) and/or MALDI-TOF mass spectrometries.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmc.2011.10.070 | DOI Listing |
Publication Analysis
Top Keywords
resorcinaren-pamam dendrimers
8
synthesis 5-aryl-14-benzodiazepine
4
5-aryl-14-benzodiazepine derivatives
4
derivatives attached
4
attached resorcinaren-pamam
4
dendrimers
4
dendrimers anti-cancer
4
anti-cancer activity
4
activity series
4
series resorcinaren-pamam
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!