Objective: To evaluate the incidence and risk factors of ROP (retinopathy of prematurity) through a prospective multicenter study.
Methods: Eleven children's or maternal & child hospitals participated in a collective network. All infants of birth weight < 2000 g, born in or transferred to one of the participating centers from January 1st 2005 to February 28th 2006 were recruited. Timely ophthalmologic examinations were performed. The relevant data at baseline and endpoints were collected at each unit.
Results: A total of 882 preterm infants fulfilled the screening criteria and 752 finished a followup. And 123 infants (16.4%) had some degree of ROP. Infants with ROP had a lower gestational age, birth weight and a longer duration of oxygen versus those without ROP [(30.82 +/- 0.20) weeks vs (32.56 +/- 0.09) weeks, (1430 +/- 25) g vs (1636 +/-10) g, (11.6 +/- 1.4) d vs (4.4 +/- 0.3) d]. Through a univariate analysis, birth weight, gestational age, asphyxia, oxygen duration > 5 days, apnea, surfactant usage, pneumonia, anemia, blood transfusion, acidosis and neonatal respiratory distress syndrome (NRDS) were associated with ROP (P < 0.05). Logistic regression analysis showed that birth weight (OR = 0.998), apnea (OR = 1.653) and blood transfusion (OR = 1.763) were independent risk factors for ROP.
Conclusion: Asphyxia, oxygen duration > 5 days, surfactant usage, anemia, acidosis and NRDS, lower birth weight, apnea and blood transfusion may improve the risks of ROP.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Gluten-free diet during pregnancy and pregnancy outcome: A retrospective cohort study.
Int J Gynaecol Obstet
January 2025
Faculty of Medicine and Health Technology, Center for Child, Adolescent, and Maternal Health Research, Tampere University, Tampere, Finland.
Objective: A gluten-free diet (GFD) is becoming increasingly popular, especially among young females, and including those without diagnosed celiac disease (CD). Whether a GFD is appropriate during pregnancy remains unclear. Our primary aim was to evaluate the association of a GFD and neonatal birthweight and incidence of large for gestational age (LGA) and small for gestational age (SGA).
View Article and Find Full Text PDFDevelopmental delay and its associated factors among children of 9 months and of 18 months attending primary health facilities in an urban resettlement area of East Delhi.
J Family Med Prim Care
December 2024
Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.
Background: Early identification of developmental delay in children can help in making early intervention for its management. Routine developmental screening is not being practised in India due to lack of trained field workers, lack of awareness among parents and lack of feasible assessment screening tool. There is lack of studies that focuses on home environment provided to the children as it is associated with developmental delay.
View Article and Find Full Text PDFSystematic Review of Interventions in Early Pregnancy Among Pregnant Individuals at Risk for Hyperglycemia.
Am J Obstet Gynecol MFM
January 2025
School of Medicine, Tufts University; Tufts Medical Center.
Objective: The maternal metabolic environment in early pregnancy can influence fetal growth trajectories. Our objective was to identify interventions initiated in early pregnancy (<20 weeks gestation) in pregnant individuals with risk factors for hyperglycemia and report their impact on primary (neonatal adiposity, small for gestational age, large for gestational age, macrosomia) and secondary outcomes (gestational weight gain, maternal hypertensive disorder, birth injury, NICU admission, preterm delivery, emergency cesarean section).
Data Sources: We searched Cochrane Central database, Medline, Embase, CINAHL databases, and clinicaltrials.
Relationship between apoptosis gene DNA methylation and fetal growth and development.
Gene
January 2025
Department of Epidemiology, School of Public Health, Center of Clinical Epidemiology and Evidence Based Medicine, Shanxi Medical University, Taiyuan, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Taiyuan, Shanxi, China. Electronic address:
Objective: To investigate the relationship between DNA methylation of cord blood apoptosis genes and low birth weight (LBW).
Methods: A case-control study was conducted on 50 pairs of LBW neonates and normal birth weight. Genome-wide methylation assay was performed using Illumina Human Methylation EPIC microarray to analyze the methylation sites of apoptosis-related genes BCL-2, CASP3, and CASP8.
Drivers of stunting and wasting across serial cross-sectional household surveys of children under 2 years of age in Pakistan: potential contribution of ecological factors.
Am J Clin Nutr
January 2025
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada; Centre for Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan; Institute for Global Health and Development, Aga Khan University, Karachi, Pakistan. Electronic address:
Background: The impact of direct and indirect drivers on linear growth and wasting in young children is of public health interest. While the contributions of poverty, maternal education, empowerment and birth weight to early childhood growth are well recognized, the contribution of environmental factors like heat, precipitation, agriculture outputs and food security in comparable datasets is less well established.
Objectives: To investigate the association of length-for-age z-score (LAZ) and weight-for-length z-score (WLZ) with various indicators among children under 2 years of age in Pakistan using representative household level nutrition surveys and ecological datasets.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!