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Digestion of food proteins: the role of pepsin.
Crit Rev Food Sci Nutr
January 2025
Riddet Institute, Massey University, Palmerston North, New Zealand.
The nutritive value of a protein is determined not only by its amino acid composition, but also by its digestibility in the gastrointestinal tract. The interaction between proteins and pepsin in the gastric stage is the first step and plays an important role in protein hydrolysis. Moreover, it affects the amino acid release rates and the allergenicity of the proteins.
View Article and Find Full Text PDFProgressive structural changes of microbial transglutaminase modified fish gelatin during gastric digestion.
Int J Biol Macromol
January 2025
National R&D Center for Freshwater Fish Processing, College of Life Science, Jiangxi Normal University, Nanchang, Jiangxi, 330022, China. Electronic address:
This study investigated the progressive structural changes of fish gelatin in thermally reversible (TR) and irreversible (TI) states, formed through microbial transglutaminase (MTGase) cross-linking during in vitro gastric digestion. The focus was on dynamic structural changes and gastric digestion characteristics. Free amino content and SDS-PAGE analyses showed that both TR and TI groups were hydrolyzed into smaller fragments by pepsin during digestion.
View Article and Find Full Text PDFHesperidin enhances broiler growth performance by augmenting gastric acid secretion via the proton pump pathway.
Poult Sci
January 2025
College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Changchun 130118, China; Jilin Key Laboratory of Animal Nutrition and Feed Science, Changchun 130118, China. Electronic address:
Hesperidin exhibits promising potential as a feed additive for augmenting gastric acid secretion in animals. Gastrointestinal function is essential for animal growth and the efficient digestion of dietary nutrients, with gastric acid secretion serving as one of its critical components. The secretion of gastric acid, together with other digestive fluids and substances, significantly influences the digestion and absorption of animal feed, which in turn affects growth performance.
View Article and Find Full Text PDFSimulated Gastrointestinal Fluids Impact the Stability of Polymer-Functionalized Selenium Nanoparticles: Physicochemical Aspects.
Int J Nanomedicine
December 2024
Division of Medical Physics and Biophysics, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, 8010, Austria.
Background: Selenium (Se) is a vital micronutrient for maintaining homeostasis in the human body. Selenium nanoparticles (SeNPs) have demonstrated improved bioavailability compared to both inorganic and organic forms of Se. Therefore, supplementing with elemental Se in its nano-form is highly promising for biomedical applications related to Se deficiency.
View Article and Find Full Text PDFExploration of the micellization behavior of sodium dodecyl sulfate in aqueous solution of gastric enzyme pepsin: Assessment of the consequences of sodium electrolytes and temperature.
Int J Biol Macromol
December 2024
Department of Chemistry, Jashore University of Science and Technology, Jashore 7408, Bangladesh. Electronic address:
This study explores the interactions between pepsin and sodium dodecyl sulfate (SDS) using conductometric analysis and molecular docking to deepen our understanding of the role of pepsin. Conductometric studies were conducted to examine the micellization behavior of SDS with pepsin in aqueous solutions of various sodium electrolytes (NaBr, Na₂SO₄, Na₃PO₄, and CH₃COONa) at temperatures ranging from 300.55 K to 320.
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