All the non-H atoms of the title compound, C(10)H(10)N(2)O(2), are nearly in the same plane with a maximum deviation of 0.093 (1) Å. In the crystal, adjacent mol-ecules are linked by pairs of inter-molecular N-H⋯O hydrogen bonds, generating inversion dimers with R(2) (2)(14) ring motifs.
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http://dx.doi.org/10.1107/S1600536811028790 | DOI Listing |
Microb Pathog
July 2024
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India; Division of Toxicology & Experimental Medicine, CSIR-Central Drug Research Institute, Lucknow, 226031, India.
The global rise of antibiotic resistance poses a substantial risk to mankind, underscoring the necessity for alternative antimicrobial options. Developing novel drugs has become challenging in matching the pace at which microbial resistance is evolving. Recently, nanotechnology, coupled with natural compounds, has emerged as a promising solution to combat multidrug-resistant bacteria.
View Article and Find Full Text PDFPLoS One
May 2024
School of Environmental Engineering, Gansu Forestry Polytechnic, Tianshui, Gansu province, People's Republic of China.
This study describes the operation of two independent parallel laboratory-scale biotrickling filters (BTFs) to degrade different types of binary volatile organic compound (VOC) mixtures. Comparison experiments were conducted to evaluate the effects of two typical VOCs, i.e.
View Article and Find Full Text PDFNutrients
March 2024
POLARIS, 29000 Quimper, France.
Docosahexaenoic acid (DHA) is an essential fatty acid (FA) with proven pro-health effects, but improving its bioavailability is becoming a public health issue. The bioavailability of DHA from microalgal (A) oil has been comprehensively assessed, particularly in terms of the molecular structuring capabilities offered by A-oil. Here, we explored the impact of five DHA-rich formulas differing in terms of (i) molecular structure, i.
View Article and Find Full Text PDFChem Res Toxicol
March 2024
Medicinal Chemistry Research Laboratory, Department of Chemistry, Shivaji University, Kolhapur, Maharashtra 416004, India.
()-Ethyl 2-cyano-3-(4'-(diphenyl amino)-[1,1'-biphenyl]-4-yl) acrylate (RSJ) is a novel luminogen based on triphenylamine. It has been fully synthesized and characterized, exhibiting an incredible photophysical phenomenon known as aggregation-induced emission (AIE). This work describes a fluorescent sensor that detects vitamin B2 in mixed aqueous media with high selectivity and a low limit of detection as well as a mechanism for reversible mechanochromic luminescence.
View Article and Find Full Text PDFOrg Biomol Chem
February 2024
Dipartimento di Farmacia-Scienze del Farmaco, Università di Bari "Aldo Moro", Consorzio C.I.N.M.P.I.S., Via E. Orabona, 4, 70125 Bari, Italy.
A new scalable synthesis of ()-α,β-unsaturated esters has been developed using protic, non-toxic, and biodegradable deep eutectic solvents through the Horner-Wadsworth-Emmons reaction between triethyl phosphonates and (hetero)aromatic carbonyl compounds, encompassing electron-withdrawing and electron-donating groups. Stereoselective preparation of disubstituted or trisubstituted ethyl cinnamate derivatives is achieved in the presence of LiOH, KCO, or DBU as bases, at room temperature and under air. Demonstrated with the synthesis of ()-ethyl 3-(4-bromophenyl)acrylate, the same eutectic mixture (choline chloride/urea) proved to be reusable for three consecutive runs.
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