AI Article Synopsis
- In vitro studies show that cranberry and its proanthocyanins can help prevent pathogens from attaching to and forming biofilms on tissues.
- Various cranberry products have been found beneficial in reducing urinary tract infections in both young and elderly women and assist in treating Helicobacter pylori infections alongside antibiotics.
- Further research is needed to isolate and identify the active components of cranberry for use in foods and products where whole juice or powder might not be practical.
Article Abstract
Summary of the in vitro data support a beneficial effect of cranberry or its proanthocyanin constituents by blocking adhesion to and biofilm formation on target tissues of pathogens. In vivo data partially support these beneficial effects. Consumption of various cranberry products benefited young and elderly females in preventing urinary tract infections, and in conjunction with antibiotic treatment in eradicating Helicobacter pylori infections in women. Mouthwash supplemented with an isolated cranberry derivative reduced significantly the caryogenic mutans streptococci. None of the mice infected intranasal with lethal dose of influenza virus and treated with cranberry fraction died after two weeks. Further studies should focus on the active cranberry component as supplement for food and other products especially where whole juice or powder cannot be used.
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| http://dx.doi.org/10.1016/j.copbio.2011.10.009 | DOI Listing |
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