AI Article Synopsis
- The study evaluates a new ultrasound technique called speckle reduction imaging (SRI) against the traditional method in diagnosing breast lesions.
- It involved 110 patients with confirmed breast tumors, where both SRI and non-SRI images were analyzed to determine their diagnostic performance using a computer-aided diagnostic system.
- Results showed no significant differences in diagnostic accuracy, sensitivity, or specificity between SRI and non-SRI, indicating that SRI does not significantly enhance the ability to differentiate benign from malignant breast masses.
Article Abstract
Purpose: Speckle reduction imaging (SRI) is a newly developed technique in ultrasound examination. This study aimed to compare the diagnostic performance of SRI and non-SRI breast ultrasound examinations by using a morphology-based computer-aided diagnostic system.
Methods: One hundred ten patients with pathologically proven breast lesions were enrolled consecutively from April 2008 to October 2008. SRI and non-SRI ultrasound images were both obtained at the same examination for each patient. The regions of interest were manually sketched by an experienced physician without histological information. Nineteen practical morphologic features from the extracted contour were calculated and a support vector machine classifier identified the breast tumor as benign or malignant. Conventional binomial receiver operating characteristics curve analysis was used to represent the diagnostic performance of both SRI and non-SRI.
Results: Between SRI and non-SRI methods, there were no significant differences in the area under the receiver operating characteristics curve (Az value: 0.82 versus 0.81), the sensitivity (78.9% versus 84.2%), and the specificity (73.6% versus 70.8%).
Conclusions: Based on the morphology study, the performance of breast ultrasound in characterizing the solid breast mass as benign or malignant was not significantly improved with SRI.
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| http://dx.doi.org/10.1002/jcu.20897 | DOI Listing |
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