We present a gelatin that fills the medullary of sternum providing effective hemostasis plus protection for each sternal end.
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Use of the D4H Probe to Track Sterols in Yeast.
Methods Mol Biol
December 2024
Institute of Functional Biology and Genomics, CSIC, University of Salamanca, Salamanca, Spain.
Cholesterol is a fundamental component of cellular membranes, and its organization, distribution, and recycling are tightly regulated. Cholesterol can form, together with other lipids and proteins, membrane nanodomains, which play important roles in membrane trafficking, the spatiotemporal organization of signal transduction, or the modulation of plasma membrane transporters, among others. Not surprisingly then, the misregulation of cholesterol biosynthetic and transport pathways has been related to numerous diseases, including neurodegenerative and metabolic disorders.
View Article and Find Full Text PDFThe 100 most-cited articles in hypothermic brain protection journals: a bibliometric and visualized analysis.
Front Neurol
November 2024
Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan Province, China.
Introduction: A bibliometric analysis is used to assess the impact of research in a particular field. However, a specialized bibliometric analysis focused on hypothermic brain protection has not yet been conducted. This study aimed to identify the 100 most-cited articles published in the field of hypothermic brain protection and analyze their bibliometric characteristics.
View Article and Find Full Text PDFSilyl- and Germyl-Substituted Boranes: Synthesis and Investigation as Potential Atomic Layer Deposition Precursors.
Inorg Chem
November 2024
Department of Chemistry, McMaster University, 1280 Main St. West, Hamilton, Ontario L8S 4M1, Canada.
Boranes featuring bulky hypersilyl or supersilyl groups and/or sterically unencumbered trimethylgermyl substituents were synthesized for investigation as potential precursors for atomic layer deposition (ALD) of elemental boron. The envisaged ALD process would employ a boron trihalide coreactant, exploiting the formation of strong silicon-halogen and germanium-halogen bonds as a driving force. The alkali metal silyl and germyl compounds hypersilyl lithium, {(MeSi)Si}Li(THF) (), supersilyl sodium, (BuSi)Na(THF) (, = 2-3), and trimethylgermyl lithium, {MeGeLi(THF)} (), were used for the synthesis of the silyl- and germyl-substituted boranes in this work.
View Article and Find Full Text PDFHeterozygous variant as a novel genetic cause of telomere biology disorders.
Genes Dev
September 2024
UMR7258 Centre National de la Recherche Scientifique (CNRS), UMR1068 Institut National de la Santé et de la Recherche Médicale (INSERM), UM105 Aix Marseille University, Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille (CRCM), Laboratoire Labellisée par la Ligue Nationale Contre le Cancer, F-13009 Marseille, France;
Premature telomere shortening or telomere instability is associated with a group of rare and heterogeneous diseases collectively known as telomere biology disorders (TBDs). Here we identified two unrelated individuals with clinical manifestations of TBDs and short telomeres associated with the identical monoallelic variant c.767A>G; Y256C in Although the replication protein A2 (RPA2) mutant did not affect ssDNA binding and G-quadruplex-unfolding properties of RPA, the mutation reduced the affinity of RPA2 with the ubiquitin ligase RFWD3 and reduced RPA ubiquitination.
View Article and Find Full Text PDFConstruction of ecological security pattern of arid area based on landscape ecological risk assessment: a case study of the Wu-Chang-Shi urban agglomeration.
Environ Sci Pollut Res Int
July 2024
School of Public Policy & Management, China University of Mining and Technology, Xuzhou, 221116, China.
The construction of ecological security pattern (ESP) holds paramount importance in ensuring regional environment sustainability. This study introduces an innovative approach to ESP construction grounded in landscape ecological risk (LER) assessment, with Wu-Chang-Shi urban agglomeration in Xinjiang, China, serving as a case study. Initially, LER within the area was evaluated using the LER Index (LERI) method.
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