Nowadays, electro-oculography remains the only clinical method for ocular movement recording which is largely used in daily practise, but it has many drawbacks and limits. Till now the photo-oculographic technics have been only applied in laboratory conditions. A new differential photo-oculographic procedure is presented. This optical method is based upon the measurement of gaze direction and ocular movement amplitude from the relative pattern of five reflected corneal dots and pupil image which are located in two different optical plans. The authors relate in detail the recording devices and processing materials for the computerized analysis of video signals. The preliminary results confirm the real advantages of the method which allows to record all sorts of ocular movements in clinical conditions.
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Clin Exp Optom
January 2025
Department of Optometry, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Clinical Relevance: The vestibular-ocular reflex stabilises the retinal image and maintains balance during head movement. Astigmatism is one of the common refractive errors that can reduce the quality of visual inputs.
Background: The purpose of this study was to investigate the effect of induced astigmatism on the function of the vestibular-ocular reflex.
Mol Cell Probes
January 2025
Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland, Mittlere Strasse 91, CH-4031. Electronic address:
The rapid advancements in the field of genetics have significantly propelled the development of gene therapies, paving the way for innovative treatments of various hereditary disorders. This review focuses on the genetics of ophthalmologic conditions, highlighting the currently approved ophthalmic gene therapy and exploring emerging therapeutic strategies under development. Inherited retinal dystrophies represent a heterogeneous group of genetic disorders that manifest across a broad spectrum from infancy to late middle age.
View Article and Find Full Text PDFBackground: Diabetic mononeuropathies, which are focal neuropathies, are less common than peripheral neuropathy in diabetes. They are frequently underreported or misdiagnosed due to mild or unnoticed cases. Early detection and treatment are crucial to prevent worsening nerve damage and complications.
View Article and Find Full Text PDFTrends Hear
January 2025
Faculty of Medicine and University Hospital Cologne, Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany.
Speech-on-speech masking is a common and challenging situation in everyday verbal communication. The ability to segregate competing auditory streams is a necessary requirement for focusing attention on the target speech. The Visual World Paradigm (VWP) provides insight into speech processing by capturing gaze fixations on visually presented icons that reflect the speech signal.
View Article and Find Full Text PDFNeurol Sci
January 2025
Center for Neurodegenerative Diseases (CEMAND), Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
Due to the variety of clinical phenotypes and the massive clinical overlap with other neurodegenerative diseases, the diagnosis of Progressive Supranuclear Palsy (PSP) remains a major challenge. Notwithstanding, early and reliable clinical diagnosis of PSP is highly warranted for estimation of prognosis, appropriate allocation to therapeutic trials and development of new diagnostic tools. As reliable biomarkers are lacking, PSP diagnosis relies on the application of the clinical criteria promoted by the International Parkinson and Movement Disorder Society (MDS).
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