Purpose: The aim of this study was to determine the mechanism of systolic anterior motion (SAM) after mitral valve (MV) repair by analyzing the clinical data of patients with MV repair.

Methods: A total of 104 MV repairs were performed for patients with isolated degenerative posterior leaflet prolapse. Eight patients (7.7%) developed SAM with severe mitral regurgitation. We compared the preoperative and intraoperative findings of the two groups (8 patients in the SAM group, 96 in the non-SAM group) and reported the clinical courses of the SAM patients.

Results: Preoperative left ventricular end-diastolic and end-systolic diameters were significantly smaller and the preoperative left ventricular ejection fraction was significantly greater in the SAM group than in the non-SAM group. The number of patients with a sigmoid septum and the number with anterior leaflet-septal contact (LSC) during diastole were significantly larger in the SAM group. Incidence of billowing posterior leaflet, prolapsed segments, and operative techniques were comparable for the two groups. SAM improved with correction of hemodynamic status in four patients. In four other patients secondary cardiopulmonary bypass was required to resolve SAM. SAM resolved with additional repairs in two patients, whereas the other two required MV replacement. Of the six patients in whom conservative treatment or re-repair was successful, one had recurrent SAM 3 months after surgery.

Conclusion: The sigmoid septum and LSC may predict SAM after MV repair. A strict follow-up is imperative for patients with persistent or recurrent SAM.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11748-011-0833-xDOI Listing

Publication Analysis

Top Keywords

sam
12
sam group
12
patients
10
systolic anterior
8
anterior motion
8
mitral valve
8
valve repair
8
posterior leaflet
8
group non-sam
8
non-sam group
8

Similar Publications

Background: Severe acute malnutrition (SAM) is a severe condition causing bilateral pitting edema or signs of wasting in children, with a high mortality risk. An outpatient therapeutic program is recommended for managing SAM children without complications, but there is limited information on recovery time and its determinants.

Objective: This study aims to assess the time to recovery and its predictors among children aged 6-59 months with SAM admitted to the Outpatient therapeutic program in the Borena zone, Oromia region, Southern Ethiopia in 2023.

View Article and Find Full Text PDF

Introduction: Many breast cancer therapeutics target the PI3K/AKT/mTOR oncogenic pathway. Development of resistance to the therapeutics targeting this pathway is a frequent occurrence. Therapeutics targeting p70S6K1, a downstream member of this pathway, have recently gained importance due to its critical role in all types of breast cancer and its status as a prognostic marker.

View Article and Find Full Text PDF

Background: Ventilator-associated pneumonia (VAP) is one of the most lethal complications in intensive care unit (ICU) patients. However, critical issues of non-survivors vary and are still unclear in VAP patients.

Methods: The clinical differences between survivors and non-survivors of VAP were retrospectively analyzed in patients hospitalized from April 2023 to March 2024.

View Article and Find Full Text PDF

Self-assembled hole-selective contact for efficient Sn-Pb perovskite solar cells and all-perovskite tandems.

Nat Commun

January 2025

College of Materials Science and Engineering & Engineering Research Center of Alternative Energy Materials & Devices, Ministry of Education, Sichuan University, Chengdu, China.

Self-assembled monolayers (SAMs) have displayed unpredictable potential in efficient perovskite solar cells (PSCs). Yet most of SAMs are largely suitable for pure Pb-based devices, precisely developing promising hole-selective contacts (HSCs) for Sn-based PSCs and exploring the underlying general mechanism are fundamentally desired. Here, based on the prototypical donor-acceptor SAM MPA-BT-BA (BT), oligoether side chains with different length (i.

View Article and Find Full Text PDF

Arsenic (As) is a toxic metalloid widespread in the environment, and its exposure has been associated with a variety of adverse health outcomes. As exposure is demonstrated to cause nonalcoholic fatty liver disease (NAFLD), and the underlying epigenetic mechanisms remain largely unknown. This study aimed to investigate the roles of histone modifications in low-level As exposure-induced NAFLD in rats.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!