Recurrent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens. We prospectively evaluated 31 patients with recurrent CA-MRSA skin infections who received nasal mupirocin, topical hexachlorophene body wash, and an oral anti-MRSA antibiotic. The mean number of MRSA infections after the intervention decreased significantly from baseline (0.03 versus 0.84 infections/month, P = <0.0001). This regimen appears promising at preventing recurrent CA-MRSA infections.
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http://dx.doi.org/10.1128/AAC.01608-10 | DOI Listing |
Infect Control Hosp Epidemiol
January 2025
Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
We surveyed 111 institutions' practices for screening and decolonization of in presurgical patients. Institutions commonly utilize universal, targeted, or no decolonization strategies. Frequently reported products were nasal mupirocin, chlorhexidine gluconate bathing, and nasal povidone-iodine.
View Article and Find Full Text PDFAm J Infect Control
January 2025
Department of Internal of Medicine, Virginia Commonwealth University Health, Richmond, VA.
Front Cell Infect Microbiol
December 2024
Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Background: The colonization of (SA) acquired in nosocomial infections may develop acute and chronic infections such as Methicillin-Resistant (MRSA) in the nose. As a commensal microorganism with the ability to form a biofilm, SA can dwell on the skin, nostrils, throat, perineum, and axillae of healthy humans. Nitric oxide (NO) is an unstable gas with various molecular functions and has antimicrobial properties which are converted into many potential treatments.
View Article and Find Full Text PDFInfect Dis (Lond)
November 2024
Department of Clinical Microbiology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Background: Throat carriage of methicillin-resistant (MRSA) has previously been associated with lower decolonisation treatment success rates.
Objectives: To characterise decolonisation treatment and outcome in Danish MRSA throat carriers.
Methods: This retrospective population-based cohort study included MRSA throat carriers between July, 2018 and June, 2019, in the Capital Region of Denmark.
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