A concise total synthesis of (±)-γ-lycorane is described. The key step in the synthesis is the 6π-electrocyclic ring closure of a divinylpyrroline to give a tetrahydroindole, which is subsequently hydrogenated to give the all-cis indolizidine core.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212046 | PMC |
| http://dx.doi.org/10.1016/j.tetlet.2011.09.138 | DOI Listing |
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