Engineered optical metamaterials present a unique platform for biosensing applications owing to their ability to confine light to nanoscale regions and to their spectral selectivity. Infrared plasmonic metamaterials are especially attractive because their resonant response can be accurately tuned to that of the vibrational modes of the target biomolecules. Here we introduce an infrared plasmonic surface based on a Fano-resonant asymmetric metamaterial exhibiting sharp resonances caused by the interference between subradiant and superradiant plasmonic resonances. Owing to the metamaterial's asymmetry, the frequency of the subradiant resonance can be precisely determined and matched to the molecule's vibrational fingerprints. A multipixel array of Fano-resonant asymmetric metamaterials is used as a platform for multispectral biosensing of nanometre-scale monolayers of recognition proteins and their surface orientation, as well as for detecting chemical binding of target antibodies to recognition proteins.
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http://dx.doi.org/10.1038/nmat3161 | DOI Listing |
Biomed Opt Express
September 2023
Light-Matter Interactions for Quantum Technologies Unit, Okinawa Institute of Science and Technology Graduate University, Onna 904-0495 Okinawa, Japan.
Strategies for in-liquid micro-organism detection are crucial for the clinical and pharmaceutical industries. While Raman spectroscopy is a promising label-free technique for micro-organism detection, it remains challenging due to the weak bacterial Raman signals. In this work, we exploit the unique electromagnetic properties of metamaterials to identify bacterial components in liquid using an array of Fano-resonant metamolecules.
View Article and Find Full Text PDFFano resonance has an asymmetric and sharp resonance peak near the resonance wavelength, enhancing optical modulation performance. Here, a Fano resonant silicon optical modulator with a micro-ring resonator (MRR) coupled with a T-shaped waveguide is designed. Compared with an MRR modulator, a Fano resonance-based modulator has a smaller wavelength range of changes in optical intensity (from 0 a.
View Article and Find Full Text PDFACS Nano
October 2022
Canary Center at Stanford for Cancer Early Detection, Stanford School of Medicine, Stanford University, Palo Alto, California 94304, United States.
Plasmonic metasurfaces consist of metal-dielectric interfaces that are excitable at background and leakage resonant modes. The sharp and plasmonic excitation profile of metal-free electrons on metasurfaces at the nanoscale can be used for practical applications in diverse fields, including optoelectronics, energy harvesting, and biosensing. Currently, Fano resonant metasurface fabrication processes for biosensor applications are costly, need clean room access, and involve limited small-scale surface areas that are not easy for accurate sample placement.
View Article and Find Full Text PDFSci Rep
January 2022
School of Electronic and Information Engineering, Beihang University, Beijing, 100191, China.
In this paper, an Asymmetric Electric Split-Ring Resonator (AESRR) metamaterial structure is proposed to explore the interaction between metamaterials and electromagnetic waves with the influence of Fano resonance on electromagnetic properties. With the symmetry of basic electric Split-Ring Resonator (eSRR) being broken, a new Fano resonant peak appears at around 11.575 GHz and this peak is very sensitive to the dielectric environment.
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