The List of Prohibited Substances and Methods (the List) is the International Standard that determines what is prohibited in sport in- and out-of-competition. The official text of the List is produced by the World Anti-Doping Agency (WADA), the international independent organization responsible for promoting, coordinating and monitoring the fight against doping in sport. The drafting of the annual List is a highly interactive and consultative process involving scientific and medical experts in anti-doping, sport federations and governments. In this article, the elements that compose the List as well as the process behind its annual revision and update are presented.
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http://dx.doi.org/10.1093/anatox/35.9.608 | DOI Listing |
Toxics
December 2024
Colleges of Forestry, Northeast Forestry University, 26 Hexing Road, Harbin 150040, China.
Organophosphorus pesticides (OPs) have become one of the most widely used pesticides in Chinese agriculture; however, methods to identify potential restrictions on OPs molecules are lacking. Therefore, this study retrieved the OPs restriction list and constructed eight multi-class, multi-category machine learning models for OPs restrictions. Among these, the random forest (RF) model demonstrated excellent predictive performance, as it was successfully validated and applied.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
School of Science, Xihua University, Chengdu 610039 PR China. Electronic address:
Beta - stimulant, that is, β - adrenergic stimulant, also known as β - agonists, is bioactive catecholamine compounds naturally produced in animals' adrenal medulla glands that induce relaxation in asthmatic airway smooth muscles upon inhalation while also temporarily boosting athletic alertness and alleviating fatigue. However, their potential for dependency poses health risks including unnoticed exacerbation leading to severe illness or fatality prompting their inclusion on WADA's prohibited substances list. Surface - enhanced Raman spectroscopy (SERS) offers a rapid, sensitive, and label - free means for identifying characteristic peaks associated with β - agonist compounds.
View Article and Find Full Text PDFBMJ Support Palliat Care
January 2025
Palliative Care, The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Patients with advanced cancer often experience bothersome symptoms requiring specialist palliative care input. Oncology clinical trials commonly include a list of prohibited medications while on trial, to avoid potential drug interactions with the investigational product. This case series illustrates how recent opioid shortages combined with prohibited opioids in clinical trials significantly impacted cancer pain control and quality of life.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Division of Diabetes and Endocrinology, Department of Pediatrics, University of Virginia, Charlottesville, VA.
Organized sports are governed by specific rules which aim to create or preserve fair play. An unfair advantage can be obtained by the use of specific substances or methods, also referred to as doping. The World Anti-Doping Agency (WADA) leads the international doping-free sport movement and annually publishes the List of Prohibited Substances and Methods (List), that is used by most sport federations and organizations around the world.
View Article and Find Full Text PDFDrug Test Anal
January 2025
Research Institute for Doping Control, Shanghai University of Sport, Shanghai, China.
Since the early 20th century, the concept of doping was first introduced. To achieve better athletic performance, chemical substances were used. By the mid-20th century, it became gradually recognized that the illegal use of doping substances can seriously endangered athletes' health and compromised the fairness of sports competitions.
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