AI Article Synopsis

  • Adiponectin levels were much lower in obese diabetic boys compared to healthy non-obese boys, indicating a potential metabolic issue (P <0.001).
  • Circulating levels of soluble E-selectin were significantly higher in the obese diabetic group, suggesting inflammation or vascular issues (P <0.01).
  • There were notable correlations showing that lower adiponectin levels are linked with higher levels of sE-selectin and other inflammatory markers, suggesting these factors might connect obesity to related health problems.

Article Abstract

Adiponectin serum levels were significantly lower in obese diabetic than in non-obese healthy boys (P <0.001). Circulating soluble E-selectin levels was significantly higher in obese diabetic boys than the healthy non-obese (P <0.01). There were significant inverse correlations between adiponectin and sE-selectin, hsCRP, IL-1b, and MCP-1 and positively with NOx. We conclude that sE-selectin and MCP-1 may represent a link between obesity and related co-morbidities in children and adults.

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