This special issue of Experimental Neurology compiles a series of papers that either explicitly replicate published studies or retest phenomena reported in previous publications. The explicit replications were carried out as part of the "Facilities of Research Excellence-Spinal Cord Injury" (FORE-SCI) program launched by the National Institute of Neurological Disorders and Stroke (NINDS) in 2003. Here, we review the FORE-SCI replication experiments published prior to those in this special issue. We then discuss emerging issues regarding replication and reproducibility in spinal cord injury research, especially in terms of potential translation to clinical trials.
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http://dx.doi.org/10.1016/j.expneurol.2011.06.017 | DOI Listing |
SLAS Technol
December 2024
Integrated Genomic Services, Research Department, Sidra Medicine, Doha, Qatar. Electronic address:
Quantitative PCR (qPCR) is a technique commonly employed in laboratories and core facilities. In our previous study, we had shown the possibility to automate steps in a panel-specific gene expression workflow by pairing Mosquito HV with BioMark HD. Here we aimed to automate the full workflow and explore miniaturization capabilities.
View Article and Find Full Text PDFIndian J Ophthalmol
January 2025
Department of Pharmacology, All India Institute of Medical Sciences, Guwahati, Assam, India.
The Schirmer strip measures tear volume in millimeters. A major limitation of the Schirmer strip is that it does not measure tear volume in a volumetric unit. Furthermore, the linearity range, lower limit of detection (LLOD), and lower limit of quantification (LLOQ) are not established.
View Article and Find Full Text PDFWaste Manag
December 2024
ETH Zurich, Laboratory of Sustainable Food Processing, Schmelzbergstrasse 9 8092, Zurich, Switzerland; Singapore-ETH Centre,1 Create Way 138602, Singapore.
Black soldier fly larvae (BSFL) efficiently convert biowaste into valuable animal feed. Sustainable and reliable bioconversion is desirable to achieve optimal economic and environmental outcomes. Thus, science and industry require an accessible research platform to study complex bioconversion processes under conditions mirroring industrial-scale settings.
View Article and Find Full Text PDFDis Model Mech
December 2024
CNRS, Institut des Neurosciences Paris-Saclay, Université Paris-Saclay, 91400 Saclay, France.
The severity of brain comorbidities in Duchenne muscular dystrophy (DMD) depends on the mutation position within the DMD gene and differential loss of distinct brain dystrophin isoforms (i.e. Dp427, Dp140, Dp71).
View Article and Find Full Text PDFEur J Pediatr
December 2024
Institute of Psychology, Faculty of Psychology and Sport Science, University of Innsbruck, Innsbruck, Austria.
The present study aims at providing reference values from the general pediatric population for the German version of the 21-item self-report post version of the Postconcussion Symptom Inventory for adolescents aged 13-17 years (PCSI-SR13) following pediatric traumatic brain injury (pTBI). A total of N = 950 adolescents completed an adapted version of the PCSI-SR13. Prior to establishing reference values using percentiles, psychometric properties (i.
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