Background: Traumatic injuries to primary teeth represent one of the most common aetiologic factors of time-related eruption disturbances of permanent teeth. These include premature eruption, delayed eruption or impactions.
Case Report: A case of a 7.5-year-old male with delayed eruption of the maxillary permanent left incisor is presented. The case history revealed a trauma around the age of 3 involving its primary tooth predecessor and its extraction by a dentist about one year later due to frequent abscesses. The clinical examination showed an early mixed dentition and the single presence of tooth 11 in the dental arch, with an obvious aesthetic problem that affected the child's self image. The periapical x-ray ruled out any dimorphism on the impacted tooth, and it showed a root developed by two thirds. About 2 months after the examination, a simple gingivectomy was carried out, and the tooth could erupt completely 3 months later without any need for orthodontic traction. One year after surgery, a complete root development could be observed, as well as the presence of the lateral incisors with a moderate crowding.
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BMC Oral Health
March 2025
Department of Orthodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China.
Background: The developmental patterns of children with cleft lip and palate (CLP) can affect the therapeutic effects. However, a consensus has not been reached on whether the development of children with CLP is delayed or advanced. We aimed to characterize the developmental patterns of children with CLP by skeletal maturation and to explore the relationship between skeletal maturation and dentition in children with CLP.
View Article and Find Full Text PDFCureus
February 2025
B2S Research Laboratory, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, MAR.
Sulfasalazine-induced hypersensitivity syndrome (SIHS) is a drug-specific variant of the syndrome known as drug reaction with eosinophilia and systemic symptoms (DRESS). It is a severe and unpredictable hypersensitivity reaction that can present with a spectrum of symptoms, ranging from mild rashes and unexplained fever to life-threatening systemic organ involvement. This diversity of symptoms often results in a diagnostic delay and/or misdiagnosis.
View Article and Find Full Text PDFAllergy Asthma Proc
March 2025
From the Division of Clinical Immunology and Allergy, Department of Internal Medicine, Necmettin Erbakan University, Meram Faculty of Medicine, Konya, Turkey and.
Rapid drug desensitization (RDD) is commonly used for immediate drug hypersensitivity reactions (DHR) across various drugs. In delayed DHRs, the conventional approach is slow desensitization; however, limitations may arise due to drug-specific or disease-related factors. With the increasing role of targeted molecular drugs in delayed DHRs, data on the efficacy of RDD in these contexts remain scarce.
View Article and Find Full Text PDFGenes (Basel)
January 2025
UOC Genetica Medica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.
Primary failure of tooth eruption (PFE) is a rare genetic disorder characterized by the failure of teeth to erupt in the absence of obvious physical obstructions, often resulting in a progressive open bite that is resistant to orthodontic treatment. While PFE can be caused by genetic or systemic factors (such as cysts, tumors, and endocrine imbalances), the non-syndromic causes are primarily genetic, with an autosomal dominant inheritance pattern with variable expressivity. Several genes have been closely associated with the non-syndromic PFE form.
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