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Tranexamic acid in hip fracture repair surgery: safe and effective?
Blood Transfus
January 2025
Département Anesthésie Réanimation, CHU Angers, Université d'Angers, Angers, France.
Intraoperative tranexamic acid reduces postoperative haemarthrosis and improves early functional outcomes in double-bundle anterior cruciate ligament reconstruction.
J Orthop
July 2025
The Department of Orthopedics Surgery, Ningbo No. 6 Hospital, Ningbo, China, 315040, 1059# ZhongShan East Road, Ningbo, Zhejiang, People's Republic of China.
Introduction: Double-bundle anterior cruciate ligament reconstruction (ACLR) has biomechanical advantages but is associated with increased intraoperative bleeding. The role of tranexamic acid (TXA) in reducing postoperative joint haemarthrosis and improving the short-term outcomes of double-bundle ACLR has not yet been thoroughly investigated. This study aimed to assess the effects of intraoperative TXA on postoperative joint haemarthrosis and short-term functional outcomes in patients who underwent double-bundle ACLR.
View Article and Find Full Text PDFOral Tranexamic Acid Treats Papulopustular Rosacea by Improving the Skin Barrier: Correspondence.
J Cosmet Dermatol
January 2025
Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
The Effects of Systemic Tranexamic Acid Administration on Drainage Volume, Length of Hospital Stay, and Postoperative Complications in Reduction Mammaplasty.
J Clin Med
December 2024
Department of Plastic, Reconstructive and Aesthetic Surgery and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), 1011 Lausanne, Switzerland.
Reduction mammaplasty is a common, elective, and safe operation, usually executed in healthy patients. Nonetheless, postoperative complications like bleeding and seroma formation can occur and significantly complicate the postoperative course. Tranexamic acid (TXA), a commonly used antifibrinolytic drug, offers a novel approach to reduce these complications.
View Article and Find Full Text PDFEfficacy and safety of topical versus intravenous tranexamic acid in spinal surgery: a systematic review and meta-analysis.
BMC Surg
January 2025
Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, 317000, China.
Background: The relative efficacies of topical and intravenous tranexamic acid (TXA) in spinal surgery remain controversial. This meta-analysis aimed to compare the efficacy and safety of topical versus intravenous TXA in spinal surgery, with a particular focus on the impacts on intraoperative blood loss (IBL) and associated outcomes.
Methods: We searched the PubMed, EMBASE, Medline, and Cochrane Library databases to identify all literature related to topical and intravenous TXA in spinal surgery.
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